NSFL1C and RPL22

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NSFL1C	RPL22
Gene Name		NSFL1 (p97) cofactor (p47)	ribosomal protein L22
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome Cytoplasm Golgi Stack Cytosol Plasma Membrane Intermediate Filament Cytoskeleton	Nucleus Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Lipid Binding Protein Phosphatase Type 1 Regulator Activity Ubiquitin Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Heparin Binding Poly(A) RNA Binding
	Biological Process	Autophagic Vacuole Assembly Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Catalytic Activity Membrane Fusion	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Alpha-beta T Cell Differentiation
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ANP32A CDK1 DBI FAM32A GLMN GSK3B LIPE NGLY1 PHAX RPL22 SRP14 STX5 TARDBP VCP	7 interactors: CALM1 CDC42 CSE1L IL7R MAPK14 NSFL1C SRPK2
Entrez ID		55968	6146
HPRD ID		09425	01602
Ensembl ID		ENSG00000088833	ENSG00000116251
Uniprot IDs		Q53FE8 Q9UNZ2	P35268
PDB IDs		1SS6	3J3B
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Regulation Of Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Intracellular Transport Cellular Localization Positive Regulation Of Protein Transport Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Protein Transport Positive Regulation Of Cellular Protein Catabolic Process Establishment Of Protein Localization Response To Endoplasmic Reticulum Stress Intracellular Protein Transport Protein Localization To Organelle Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Transport Nucleocytoplasmic Transport Nuclear Transport Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Proteolysis Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Pronuclear Fusion Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Heat Positive Regulation Of Transport Positive Regulation Of Proteasomal Protein Catabolic Process Muscle Cell Differentiation Regulation Of Protein Localization Organelle Fusion Cellular Macromolecule Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development SnRNA Export From Nucleus Superior Temporal Gyrus Development Membrane Organization SRP-dependent Cotranslational Protein Targeting To Membrane Triglyceride Metabolic Process Cotranslational Protein Targeting To Membrane ER To Golgi Vesicle-mediated Transport Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Neutral Lipid Metabolic Process Re-entry Into Mitotic Cell Cycle Golgi Disassembly Negative Regulation Of Neuron Maturation	Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response Innate Immune Response Substantia Nigra Development Regulation Of Immune Response Leukocyte Differentiation Angiogenesis Neural Nucleus Development Immune System Process Regulation Of Cytokinesis Positive Regulation Of Neuron Apoptotic Process Blood Coagulation Blood Vessel Morphogenesis Hemostasis Regulation Of Intracellular Transport Positive Regulation Of Neuron Death Golgi Organization Immune Response-regulating Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Midbrain Development Regulation Of Immune System Process Positive Regulation Of Kinase Activity Growth Nuclear Speck Organization P38MAPK Cascade Defense Response Blood Vessel Development Vasculature Development Positive Regulation Of Transferase Activity Regulation Of Body Fluid Levels Myeloid Leukocyte Differentiation Wound Healing Positive Regulation Of Gene Expression Nucleus Organization Interleukin-7-mediated Signaling Pathway Positive Regulation Of Hair Follicle Cell Proliferation Hemopoiesis Organelle Organization Cellular Response To Radiation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Glucose Metabolic Process Response To Wounding Immune System Development Submandibular Salivary Gland Formation Actin Filament Branching Regulation Of Muscle Cell Differentiation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Intracellular Protein Transport Positive Regulation Of Transport
Tagcloud ?		anxa4 cacybp cfl1 ciapin1 ctro cytokinesis fam50a hspb1 incapable mefs migrated nbs ndrg ndrg1 ndrg1expression pcbp2 pdap1 pml proliferate proliferated relay rsu1 stations stmn1 sumo2 tpd52l2 trio ube2m ywhag	apocytochrome infa l20 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl20 rpl23 rpl33 rpoa rps11 rps12 rps18 rps3 rps8 secx ugg
Tagcloud (Difference) ?		anxa4 cacybp cfl1 ciapin1 ctro cytokinesis fam50a hspb1 incapable mefs migrated nbs ndrg ndrg1 ndrg1expression pcbp2 pdap1 pml proliferate proliferated relay rsu1 stations stmn1 sumo2 tpd52l2 trio ube2m ywhag	apocytochrome infa l20 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl20 rpl23 rpl33 rpoa rps11 rps12 rps18 rps3 rps8 secx ugg
Tagcloud (Intersection) ?