TRERF1 and NR5A1

Number of citations of the paper that reports this interaction (PMID 12101186)
9

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TRERF1	NR5A1
Gene Name		transcriptional regulating factor 1	nuclear receptor subfamily 5, group A, member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding DNA Binding, Bending Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Metal Ion Binding	DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Phospholipid Binding Zinc Ion Binding Enzyme Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Steroid Biosynthetic Process Cholesterol Catabolic Process Multicellular Organismal Development Homeostatic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Hormone Biosynthetic Process	Luteinization Transcription Initiation From RNA Polymerase II Promoter Cell-cell Signaling Primary Sex Determination Male Gonad Development Tissue Development Multicellular Organismal Aging Gene Expression Cell Differentiation Adrenal Gland Development Intracellular Receptor Signaling Pathway Hormone Metabolic Process Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Steroid Biosynthetic Process Maintenance Of Protein Location In Nucleus Positive Regulation Of Male Gonad Development Negative Regulation Of Female Gonad Development
Pathways			Transcriptional regulation of pluripotent stem cells Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CREBBP EP300 NR5A1	28 interactors: AR CREBBP CTNNB1 CXXC1 EDF1 GATA4 GTF2B JUN MAPK1 NCK2 NCOA1 NFKB2 NFYA NR0B1 NRIP1 PIAS1 PITX1 PNRC2 PROX1 RAD54L2 SMARCD3 SOX2 SOX8 SOX9 SP1 TBX19 TRERF1 ZNF653
Entrez ID		55809	2516
HPRD ID		11647	01702
Ensembl ID		ENSG00000124496	ENSG00000136931
Uniprot IDs		Q05GC8 Q96PN7	F1D8R8 Q13285
PDB IDs			1YOW 1ZDT
Enriched GO Terms of Interacting Partners?		N-terminal Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Rhythmic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Heat Positive Regulation Of Type I Interferon Production Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Type I Interferon Production Cellular Response To Oxygen Levels Response To Heat Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Acetylation Notch Signaling Pathway Histone H2B Acetylation Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Response To Temperature Stimulus Positive Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Peptidyl-lysine Modification Response To Hypoxia Primary Sex Determination Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Tubulin Deacetylation Negative Regulation Of Female Gonad Development Germ-line Stem Cell Maintenance Positive Regulation Of Cytokine Production Histone Modification Transcription, DNA-templated RNA Biosynthetic Process Response To Steroid Hormone Positive Regulation By Host Of Viral Transcription Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Male Gonad Development Regulation Of Female Gonad Development Regulation Of Cytokine Production Viral Process Luteinization	Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Gland Development Reproductive Structure Development Reproductive System Development Sex Differentiation Regulation Of Cell Differentiation Positive Regulation Of Cell Proliferation Regulation Of Cell Proliferation Developmental Process Involved In Reproduction Multicellular Organismal Development Androgen Receptor Signaling Pathway Cell Fate Commitment Embryonic Morphogenesis Male Sex Differentiation Rhythmic Process Cell Differentiation Organ Development Single Organism Reproductive Process Regulation Of Cellular Process Glial Cell Fate Commitment Camera-type Eye Morphogenesis Developmental Process Anatomical Structure Development
Tagcloud ?			attracted bisphenol bpa durations esr estrogenic expressions flanking gobiocypris inhibitive involve minnow monomer mug nominal obviously oocyte ovarian ovary rarus reproduction researchers steroidogenesis steroidogenic stimulative subfamily suppressive vitellogenin vtg
Tagcloud (Difference) ?			attracted bisphenol bpa durations esr estrogenic expressions flanking gobiocypris inhibitive involve minnow monomer mug nominal obviously oocyte ovarian ovary rarus reproduction researchers steroidogenesis steroidogenic stimulative subfamily suppressive vitellogenin vtg
Tagcloud (Intersection) ?