EXOC2 and EXOC8

Number of citations of the paper that reports this interaction (PMID 14525976)
66

Data Source:
BioGRID (affinity chromatography technology, biochemical, affinity chromatography technology)
HPRD (two hybrid, in vitro, in vivo)

		EXOC2	EXOC8
Gene Name		exocyst complex component 2	exocyst complex component 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone
	Molecular Function	Protein Binding Ral GTPase Binding Protein Kinase Binding Protein N-terminus Binding	Protein Binding Ral GTPase Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Exocyst Assembly Organelle Organization Endosome Organization Protein Transport Extracellular Matrix Disassembly Cellular Protein Metabolic Process Exocyst Localization Membrane Organization
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing	Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Basal cell carcinoma ( 21700618) Black vs. blond hair color ( 18483556) Black vs. red hair color ( 18483556) Dental caries ( 23064961) Non-melanoma skin cancer ( 23548203) Schizophrenia ( 22885689) Tanning ( 19340012)
Protein-Protein Interactions		7 interactors: ESX1 EXOC3 EXOC7 EXOC8 RALA SERGEF VPS53	20 interactors: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA TADA2A ULK1 USHBP1
Entrez ID		55770	149371
HPRD ID		11544	09943
Ensembl ID		ENSG00000112685	ENSG00000116903
Uniprot IDs		B2RBE6 Q96KP1	Q8IYI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocyst Localization Exocytosis Secretion By Cell Cellular Protein Complex Localization Protein Complex Localization Vesicle-mediated Transport Secretion Membrane Organization Establishment Of Localization In Cell Cellular Localization Exocyst Assembly Protein Transport Establishment Of Protein Localization Membrane Raft Localization Protein Localization Positive Regulation Of Ran GTPase Activity Transport Labyrinthine Layer Morphogenesis	Organelle Organization Protein Localization Post-Golgi Vesicle-mediated Transport Cytoskeleton Organization Golgi To Plasma Membrane Transport Membrane Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Microtubule Anchoring Histone H3 Acetylation Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Golgi Vesicle Transport Cellular Localization Cytoplasmic Transport Radial Glia Guided Migration Of Cerebellar Granule Cell Exocytosis Establishment Of Localization In Cell Membrane Raft Localization Protein Transport Histone Acetylation Vesicle-mediated Transport Establishment Of Protein Localization Internal Peptidyl-lysine Acetylation Regulation Of Tubulin Deacetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Intracellular Transport Maintenance Of Protein Location In Cell Intraciliary Transport Involved In Cilium Morphogenesis Secretion Of Lysosomal Enzymes Microtubule-based Transport Protein Acetylation Maintenance Of Protein Location Regulation Of Cell Differentiation Cytoskeleton-dependent Intracellular Transport Maintenance Of Location In Cell Organelle Assembly Negative Regulation Of Collateral Sprouting
Tagcloud ?		agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1
Tagcloud (Difference) ?		agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1
Tagcloud (Intersection) ?