EXOC2 and VPS53

Number of citations of the paper that reports this interaction (PMID 20685960)
14

Data Source:
BioGRID (two hybrid)

		EXOC2	VPS53
Gene Name		exocyst complex component 2	vacuolar protein sorting 53 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle	GARP Complex Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ral GTPase Binding Protein Kinase Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Protein Transport Retrograde Transport, Endosome To Golgi
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Basal cell carcinoma ( 21700618) Black vs. blond hair color ( 18483556) Black vs. red hair color ( 18483556) Dental caries ( 23064961) Non-melanoma skin cancer ( 23548203) Schizophrenia ( 22885689) Tanning ( 19340012)	Prostate cancer ( 23535732)
Protein-Protein Interactions		7 interactors: ESX1 EXOC3 EXOC7 EXOC8 RALA SERGEF VPS53	4 interactors: EXOC2 VPS51 VPS52 VPS54
Entrez ID		55770	55275
HPRD ID		11544	07720
Ensembl ID		ENSG00000112685	ENSG00000141252
Uniprot IDs		B2RBE6 Q96KP1	B3KS06 Q5VIR6
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocyst Localization Exocytosis Secretion By Cell Cellular Protein Complex Localization Protein Complex Localization Vesicle-mediated Transport Secretion Membrane Organization Establishment Of Localization In Cell Cellular Localization Exocyst Assembly Protein Transport Establishment Of Protein Localization Membrane Raft Localization Protein Localization Positive Regulation Of Ran GTPase Activity Transport Labyrinthine Layer Morphogenesis	Post-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Golgi To Plasma Membrane Transport Protein Transport Establishment Of Protein Localization Protein Localization Retrograde Transport, Endosome To Golgi Cytoplasmic Transport Embryonic Ectodermal Digestive Tract Development Endosomal Transport Vesicle-mediated Transport Ectodermal Cell Differentiation Intracellular Transport Golgi To Vacuole Transport Transport Establishment Of Localization In Cell Neurofilament Cytoskeleton Organization Cellular Localization Ectoderm Development Homeostasis Of Number Of Cells Within A Tissue Intermediate Filament Cytoskeleton Organization Embryonic Digestive Tract Development Intermediate Filament-based Process Musculoskeletal Movement Vacuolar Transport Digestive Tract Development Digestive System Development
Tagcloud ?		agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps52 vps54 wobbler
Tagcloud (Difference) ?		agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps52 vps54 wobbler
Tagcloud (Intersection) ?