EXOC2 and SERGEF

Number of citations of the paper that reports this interaction (PMID 12459492)
1

Data Source:
HPRD (in vitro, two hybrid)

		EXOC2	SERGEF
Gene Name		exocyst complex component 2	secretion regulating guanine nucleotide exchange factor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleolus Cytoplasm Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Ral GTPase Binding Protein Kinase Binding Protein N-terminus Binding	Ran Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Signal Transduction Positive Regulation Of Ran GTPase Activity Negative Regulation Of Protein Secretion
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Basal cell carcinoma ( 21700618) Black vs. blond hair color ( 18483556) Black vs. red hair color ( 18483556) Dental caries ( 23064961) Non-melanoma skin cancer ( 23548203) Schizophrenia ( 22885689) Tanning ( 19340012)
Protein-Protein Interactions		7 interactors: ESX1 EXOC3 EXOC7 EXOC8 RALA SERGEF VPS53	4 interactors: DPH3 EXOC2 KDM1A PRMT6
Entrez ID		55770	26297
HPRD ID		11544	06926
Ensembl ID		ENSG00000112685	ENSG00000129158
Uniprot IDs		B2RBE6 Q96KP1	A8K8C1 Q9UGK8
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocyst Localization Exocytosis Secretion By Cell Cellular Protein Complex Localization Protein Complex Localization Vesicle-mediated Transport Secretion Membrane Organization Establishment Of Localization In Cell Cellular Localization Exocyst Assembly Protein Transport Establishment Of Protein Localization Membrane Raft Localization Protein Localization Positive Regulation Of Ran GTPase Activity Transport Labyrinthine Layer Morphogenesis	Regulation Of Primitive Erythrocyte Differentiation Histone H3-R2 Methylation Regulation Of Binding Cellular Protein Metabolic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Histone Modification Positive Regulation Of Megakaryocyte Differentiation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Histone H4-R3 Methylation Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Peptidyl-arginine N-methylation Protein Metabolic Process Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Histone Arginine Methylation Chromatin Modification Peptidyl-arginine Methylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Chromatin Organization Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Golgi To Plasma Membrane Transport Histone Demethylation Regulation Of Erythrocyte Differentiation Protein Demethylation Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Binding Organelle Organization Cellular Protein Modification Process Peptidyl-amino Acid Modification Regulation Of Histone Methylation Positive Regulation Of Neural Precursor Cell Proliferation Pituitary Gland Development Negative Regulation Of Protein Binding Chromosome Organization
Tagcloud ?		agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1
Tagcloud (Difference) ?		agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1
Tagcloud (Intersection) ?