GPATCH2L and PDLIM7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPATCH2L	PDLIM7
Description		G-patch domain containing 2 like	PDZ and LIM domain 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Stress Fiber Ruffle Nucleoplasm Cytoplasm Cytosol Cytoskeleton Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin
	Molecular Function	Protein Binding	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process		Ossification Receptor-mediated Endocytosis Heart Development Actin Cytoskeleton Organization Cell Differentiation Muscle Structure Development
Pathways			RET signaling
Drugs
Diseases
GWAS		Declining hemoglobin trajectory in blood donors ( 33491795) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494)	Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		46 interacting genes: APP BATF3 CARD10 CCDC33 CEP70 CYSRT1 DIP2A HSF2BP KDM1A KRT40 KRTAP10-9 KRTAP4-12 LMO1 LMO3 LZTS2 MAB21L3 MDFI MEOX2 NAA10 NDUFB7 PDLIM7 PLAGL2 PNMA2 PRDM14 PRMT1 PRMT8 PSME3 RBM11 RBPMS SUV39H1 THAP1 TLE5 TRIB3 TRIM41 TSPYL1 TULP3 ZBTB48 ZBTB8A ZNF165 ZNF263 ZNF398 ZNF408 ZNF473 ZNF526 ZNF547 ZNF837	63 interacting genes: ABI2 AP5B1 ATOSB BAG3 BSG CATSPER1 CCDC185 DDX6 DGCR6 DNER ENKD1 FAM90A1 FNDC11 FRS3 GARIN6 GEM GFAP GPATCH2L HEY2 HNRNPD HNRNPF HSF2BP HSPB7 IL16 IQGAP1 KANK2 MDM2 NUDT10 OTUD6A PAK5 PARVG PCBP1 PHF1 PIN1 PLEKHN1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RASGEF1B RET RPP25 SCNM1 SH2B2 SH3BP2 SLAIN1 SMURF1 SNCA SPP1 TCF19 TNPO2 TP53 TPM2 TRAF2 TRAF3 TSG101 TSGA10IP UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		55668	9260
HPRD ID		16594	10436
Ensembl ID		ENSG00000089916	ENSG00000196923
Uniprot IDs		Q9NWQ4	Q9NR12
PDB IDs			2Q3G 7RM8
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Nucleus Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Identical Protein Binding Regulation Of Metabolic Process Zinc Ion Binding Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation DNA Binding Enzyme Binding Histone Methyltransferase Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein-arginine N-methyltransferase Activity Negative Regulation Of RNA Metabolic Process Metal Ion Binding	Protein Binding Diacylglycerol-dependent Serine/threonine Kinase Activity Histone H3T6 Kinase Activity Striated Muscle Cell Apoptotic Process Cellular Response To Actinomycin D Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Muscle Cell Apoptotic Process Response To Actinomycin D Protein Kinase C Signaling Cellular Response To UV-C Regulation Of MAPK Cascade Signaling Adaptor Activity Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Transport Regulation Of Protein Metabolic Process Regulation Of Chaperone-mediated Autophagy Regulation Of Programmed Cell Death Histone H3K36me3 Reader Activity Actin Filament Apoptotic Process Regulation Of Gene Expression Cytoplasmic Side Of Plasma Membrane Supramolecular Fiber Organization Negative Regulation Of Catabolic Process Enzyme Binding Programmed Cell Death Negative Regulation Of Signal Transduction Regulation Of Apoptotic Process Cellular Response To Antibiotic Cell Death Negative Regulation Of Programmed Cell Death Mitotic Nuclear Membrane Disassembly Negative Regulation Of Glial Cell Apoptotic Process Thioesterase Binding CD40 Receptor Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?