UBE2Q1 and RNF7

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		UBE2Q1	RNF7
Gene Name		ubiquitin-conjugating enzyme E2Q family member 1	ring finger protein 7
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Filopodium	Nucleus Nucleoplasm Cytoplasm Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding ATP Binding Ligase Activity	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Cullin Family Protein Binding
	Biological Process	Suckling Behavior Embryo Implantation Mating Behavior Fertilization Protein Ubiquitination Reproductive System Development Prolactin Secretion	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Protein Ubiquitination Negative Regulation Of Apoptotic Process Protein Neddylation Response To Redox State
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Hepatitis C induced liver fibrosis ( 22841784)
Protein-Protein Interactions		6 interactors: FHL3 IRF2BPL KIAA0368 RNF26 RNF7 STUB1	34 interactors: ASB2 CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS GEM GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L NFKBIA PLA2G15 TCEB1 TCEB2 TRIM46 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2M UBE2Q1
Entrez ID		55585	9616
HPRD ID		15601	04840
Ensembl ID		ENSG00000160714
Uniprot IDs		Q29SN7 Q7Z7E8	Q9UBF6
PDB IDs		2QGX	2ECL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Chaperone-mediated Protein Complex Assembly	Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Protein Metabolic Process Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Viral Process Regulation Of DNA-templated Transcription In Response To Stress Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Proteolysis Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Protein K48-linked Ubiquitination Protein Monoubiquitination Positive Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Cell Cycle Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Process Negative Regulation Of Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Cell Cycle Apoptotic Signaling Pathway Apoptotic Process Cellular Response To Oxygen Levels Positive Regulation Of Metabolic Process Cellular Response To Stimulus Programmed Cell Death Cellular Metabolic Process Cell Death Death Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Response To Abiotic Stimulus Proteasomal Protein Catabolic Process Cell Cycle Arrest TRIF-dependent Toll-like Receptor Signaling Pathway
Tagcloud ?			biologically bridges consistently cul degraded e3 etoposide hect ligase ligases list nedd4 proteasome rbx2 redox ring roc2 sag scf sensitizes shortened substrates terminus transcriptionally tri ubiquitin ubiquitylated ubiquitylates ubiquitylation
Tagcloud (Difference) ?			biologically bridges consistently cul degraded e3 etoposide hect ligase ligases list nedd4 proteasome rbx2 redox ring roc2 sag scf sensitizes shortened substrates terminus transcriptionally tri ubiquitin ubiquitylated ubiquitylates ubiquitylation
Tagcloud (Intersection) ?