UBE2Q1

Description		ubiquitin conjugating enzyme E2 Q1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Filopodium Cell Projection
	Molecular Function	Nucleotide Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Suckling Behavior Embryo Implantation Mating Behavior Fertilization Protein Ubiquitination Reproductive System Development Prolactin Secretion
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
Interacting Genes		13 interacting genes: ECPAS FHL3 IRF2BPL ITCH LMNA MDM2 OGT RNF26 RNF31 RNF7 STUB1 TP53 UBC
Entrez ID		55585
HPRD ID		15601
Ensembl ID		ENSG00000160714
Uniprot IDs		Q7Z7E8
PDB IDs		2QGX
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Regulation Of Programmed Necrotic Cell Death Post-translational Protein Modification Protein Polyubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification Process Proteolysis Negative Regulation Of Signal Transduction Ubiquitin Protein Ligase Binding Modification-dependent Protein Catabolic Process Cellular Response To Actinomycin D Catabolic Process Regulation Of Necroptotic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Cell Communication Negative Regulation Of Signaling NEDD8 Ligase Activity Response To Actinomycin D Protein Metabolic Process Macromolecule Catabolic Process Cellular Response To Oxygen Levels Cellular Response To UV-C Transferase Activity Proteasomal Protein Catabolic Process Protein Autoubiquitination Response To Endoplasmic Reticulum Stress Cellular Response To Antibiotic Negative Regulation Of Programmed Cell Death Ubiquitin-protein Transferase Activity Regulation Of Programmed Cell Death Ubiquitin-dependent Protein Catabolic Process Macromolecule Metabolic Process Response To UV-C Response To Hypoxia Nucleoplasm Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ubiquitin-ubiquitin Ligase Activity Response To Decreased Oxygen Levels Negative Regulation Of Defense Response To Virus Response To Stress Response To Oxygen Levels Negative Regulation Of Cellular Component Organization Regulation Of Protein Stability Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Protein Catabolic Process
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