UBE2Q1 and IRF2BPL

Number of citations of the paper that reports this interaction (PMID 19690564)
33

Data Source:
BioGRID (two hybrid)

		UBE2Q1	IRF2BPL
Gene Name		ubiquitin-conjugating enzyme E2Q family member 1	interferon regulatory factor 2 binding protein-like
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Filopodium	Extracellular Space Nucleus Nucleoplasm
	Molecular Function	Protein Binding ATP Binding Ligase Activity	Molecular_function Metal Ion Binding
	Biological Process	Suckling Behavior Embryo Implantation Mating Behavior Fertilization Protein Ubiquitination Reproductive System Development Prolactin Secretion	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Development Of Secondary Female Sexual Characteristics
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Adverse response to lamotrigine and phenytoin ( 22379998)
Protein-Protein Interactions		6 interactors: FHL3 IRF2BPL KIAA0368 RNF26 RNF7 STUB1	2 interactors: HCK UBE2Q1
Entrez ID		55585	64207
HPRD ID		15601	10713
Ensembl ID		ENSG00000160714	ENSG00000119669
Uniprot IDs		Q29SN7 Q7Z7E8	Q9H1B7
PDB IDs		2QGX	2B9G 2CS3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Chaperone-mediated Protein Complex Assembly	Respiratory Burst After Phagocytosis Leukocyte Migration Involved In Immune Response Respiratory Burst Involved In Defense Response Secretion By Cell Prolactin Secretion Regulation Of Podosome Assembly Secretion Respiratory Burst Positive Regulation Of Actin Cytoskeleton Reorganization Suckling Behavior Regulation Of Defense Response To Virus By Virus Mating Behavior Peptidyl-tyrosine Autophosphorylation Lipopolysaccharide-mediated Signaling Pathway Regulation Of Actin Cytoskeleton Reorganization Leukocyte Degranulation Mating Regulated Secretory Pathway Regulation Of Phagocytosis Peptide Hormone Secretion Defense Response To Gram-positive Bacterium Peptide Secretion
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