SVOP and FXYD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SVOP	FXYD6
Description		SV2 related protein	FXYD domain containing ion transport regulator 6
Image		No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Basal Plasma Membrane Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse	Plasma Membrane Membrane Presynaptic Membrane Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process	Xenobiotic Transport Transmembrane Transport	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Regulation Of Monoatomic Ion Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane
Pathways			Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS			Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)
Interacting Genes		7 interacting genes: CCR2 CLK1 CYSLTR2 FXYD6 GLP1R OGT TAAR1	67 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35E1 SLC35E3 SLC35H1 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119
Entrez ID		55530	53826
HPRD ID		13224	09456
Ensembl ID		ENSG00000166111	ENSG00000137726
Uniprot IDs		Q8N4V2	Q9H0Q3
PDB IDs			8D3U 8D3V 8D3W 8D3X 8D3Y
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Glucagon-like Peptide 1 Receptor Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cysteinyl Leukotriene Receptor Activity G Protein-coupled Amine Receptor Activity Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Chemokine (C-C Motif) Ligand 12 Binding Chemokine (C-C Motif) Ligand 2 Binding Positive Regulation Of Cold-induced Thermogenesis Trace-amine Receptor Activity Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Positive Regulation Of Thymocyte Migration Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Chemokine (C-C Motif) Ligand 7 Binding Positive Regulation Of Hematopoietic Stem Cell Migration Regulation Of Astrocyte Chemotaxis Glucagon Receptor Activity Protein O-acetylglucosaminyltransferase Activity Leukotriene Receptor Activity Regulation Of Thymocyte Migration Regulation Of Immune Complex Clearance By Monocytes And Macrophages Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Cold-induced Thermogenesis Leukotriene Signaling Pathway CCR2 Chemokine Receptor Binding Positive Regulation Of T Cell Extravasation Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Response To Psychosocial Stress Plasma Membrane Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Monocyte Extravasation Monocyte Extravasation Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Hemopoiesis Neutrophil Clearance Carbon Catabolite Regulation Of Transcription Ion Channel Regulator Activity Galanin Receptor Activity Post-translational Protein Targeting To Membrane, Translocation Positive Regulation Of Sodium Ion Export Across Plasma Membrane Regulation Of Transcription By Glucose Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Glutamate Receptor Signaling Pathway	Membrane Transmembrane Transport Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Antiporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid
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