SVOP and TAAR1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		SVOP	TAAR1
Description		SV2 related protein	trace amine associated receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Basal Plasma Membrane Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Trace-amine Receptor Activity G Protein-coupled Receptor Activity G Protein-coupled Amine Receptor Activity
	Biological Process	Xenobiotic Transport Transmembrane Transport	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Pathways			Amine ligand-binding receptors G alpha (s) signalling events
Drugs			Amphetamine Lisdexamfetamine Dextroamphetamine Metamfetamine Propylhexedrine SEP-363856
Diseases
GWAS			Compulsion score in obsessive compulsive disorder ( 32063569)
Interacting Genes		7 interacting genes: CCR2 CLK1 CYSLTR2 FXYD6 GLP1R OGT TAAR1	4 interacting genes: GRIK1 PCMT1 RNASEK SVOP
Entrez ID		55530	134864
HPRD ID		13224	18142
Ensembl ID		ENSG00000166111	ENSG00000146399
Uniprot IDs		Q8N4V2	Q96RJ0
PDB IDs			8JLN 8JLO 8JLP 8JLQ 8JLR 8JSO 8UHB 8W87 8W88 8W89 8W8A 8WC8 8WCA 8ZSJ 8ZSP 8ZSS 9JKQ
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Glucagon-like Peptide 1 Receptor Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cysteinyl Leukotriene Receptor Activity G Protein-coupled Amine Receptor Activity Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Chemokine (C-C Motif) Ligand 12 Binding Chemokine (C-C Motif) Ligand 2 Binding Positive Regulation Of Cold-induced Thermogenesis Trace-amine Receptor Activity Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Positive Regulation Of Thymocyte Migration Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Chemokine (C-C Motif) Ligand 7 Binding Positive Regulation Of Hematopoietic Stem Cell Migration Regulation Of Astrocyte Chemotaxis Glucagon Receptor Activity Protein O-acetylglucosaminyltransferase Activity Leukotriene Receptor Activity Regulation Of Thymocyte Migration Regulation Of Immune Complex Clearance By Monocytes And Macrophages Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Cold-induced Thermogenesis Leukotriene Signaling Pathway CCR2 Chemokine Receptor Binding Positive Regulation Of T Cell Extravasation Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Response To Psychosocial Stress Plasma Membrane Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Monocyte Extravasation Monocyte Extravasation Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Hemopoiesis Neutrophil Clearance Carbon Catabolite Regulation Of Transcription Ion Channel Regulator Activity Galanin Receptor Activity Post-translational Protein Targeting To Membrane, Translocation Positive Regulation Of Sodium Ion Export Across Plasma Membrane Regulation Of Transcription By Glucose Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Glutamate Receptor Signaling Pathway	Glutamate-gated Calcium Ion Channel Activity Glutamate-gated Receptor Activity Kainate Selective Glutamate Receptor Complex Transmembrane Transport Kainate Selective Glutamate Receptor Activity Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity Protein Repair Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain Endosomal Lumen Acidification Endocytosis Involved In Viral Entry Into Host Cell Receptor-mediated Endocytosis Of Virus By Host Cell Proton-transporting V-type ATPase Complex Ionotropic Glutamate Receptor Signaling Pathway Ligand-gated Monoatomic Ion Channel Activity Protein Methylation Lysosomal Lumen Acidification Clathrin-coated Vesicle Membrane RNA Endonuclease Activity Regulation Of Lysosomal Lumen PH Vacuolar Acidification Synaptic Transmission, Glutamatergic Ligand-gated Ion Channel Signaling Pathway Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Xenobiotic Transport
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