MNS1 and GIGYF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MNS1	GIGYF1
Description		meiosis specific nuclear structural 1	GRB10 interacting GYF protein 1
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Cytoskeleton Axonemal Microtubule Intermediate Filament Cilium Axoneme Nuclear Speck Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Polymeric Cytoskeletal Fiber Axonemal A Tubule Inner Sheath	Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Spermatogenesis Sperm Axoneme Assembly Flagellated Sperm Motility Cilium Organization Positive Regulation Of Cilium Assembly Meiotic Cell Cycle Left/right Axis Specification	Insulin-like Growth Factor Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Chronic lymphocytic leukemia ( 23770605 26956414) Clozapine-induced agranulocytosis ( 25187353) Hematology traits ( 30576415) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Autoimmune thyroid disease ( 32581359) LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Resting heart rate ( 27798624)
Interacting Genes		24 interacting genes: CCND3 CDR2 CEP63 DISC1 EP400 EWSR1 FCHSD2 GIGYF1 IQCB1 KDM1A KIAA0753 KRT34 KRT75 PICK1 RSPH14 SNX32 STMN3 THOC7 TNNI1 TNNI2 TRIM54 TXLNB USHBP1 ZMYND12	33 interacting genes: AIRIM ANKRD10 ARMC7 ATN1 CBX8 CCDC57 CNOT9 CRACR2A ENKD1 FAM124B GRB10 GRB14 GRB7 KAT5 KIFC3 MCRS1 MNS1 NEK6 NFKBID PRKAA2 PRR35 RBM22 SCAF8 SCNM1 SMARCD1 SNRPB SNRPC SPAG8 STAC3 TCEA2 TLE5 TROAP TSHZ2
Entrez ID		55329	64599
HPRD ID		10967	10145
Ensembl ID		ENSG00000138587	ENSG00000146830
Uniprot IDs		B3KQ70 Q8NEH6	O75420
PDB IDs		7UNG 8J07	5NVK 7RUQ
Enriched GO Terms of Interacting Partners?		Troponin Complex Cytosolic Ciliogenesis	Nucleoplasm Spliceosomal Complex Negative Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Insulin Receptor Signaling Pathway Lipid Droplet Disassembly Phosphatidylethanolamine Biosynthetic Process Positive Regulation Of DNA Repair Spindle Pole Protein Binding Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus Insulin Receptor Signaling Pathway MRNA Splicing, Via Spliceosome U2-type Prespliceosome RNA Splicing U1 SnRNP Microtubule-based Process RNA Splicing, Via Transesterification Reactions Phosphatidylcholine Biosynthetic Process Regulation Of DNA Repair MRNA Metabolic Process Histone Acetyltransferase Complex Axonemal A Tubule Inner Sheath Positive Regulation Of Cation Channel Activity
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