MNS1 and IQCB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MNS1	IQCB1
Description		meiosis specific nuclear structural 1	IQ motif containing B1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Cytoskeleton Axonemal Microtubule Intermediate Filament Cilium Axoneme Nuclear Speck Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Polymeric Cytoskeletal Fiber Axonemal A Tubule Inner Sheath	Photoreceptor Outer Segment Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Calmodulin Binding Enzyme Binding Protein-macromolecule Adaptor Activity BBSome Binding
	Biological Process	Spermatogenesis Sperm Axoneme Assembly Flagellated Sperm Motility Cilium Organization Positive Regulation Of Cilium Assembly Meiotic Cell Cycle Left/right Axis Specification	Cell Projection Organization Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Cytosolic Ciliogenesis
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Senior-Loken syndrome
GWAS		A body shape index ( 34021172) Chronic lymphocytic leukemia ( 23770605 26956414) Clozapine-induced agranulocytosis ( 25187353) Hematology traits ( 30576415) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Hemoglobin levels ( 32327693) Multiple sclerosis ( 24076602 31604244) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)
Interacting Genes		24 interacting genes: CCND3 CDR2 CEP63 DISC1 EP400 EWSR1 FCHSD2 GIGYF1 IQCB1 KDM1A KIAA0753 KRT34 KRT75 PICK1 RSPH14 SNX32 STMN3 THOC7 TNNI1 TNNI2 TRIM54 TXLNB USHBP1 ZMYND12	12 interacting genes: CALM2 CALML3 KIF9 LDOC1 MARCHF7 MNS1 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TRIM32
Entrez ID		55329	9657
HPRD ID		10967	11049
Ensembl ID		ENSG00000138587	ENSG00000173226
Uniprot IDs		B3KQ70 Q8NEH6	Q15051
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		Troponin Complex Cytosolic Ciliogenesis	Detection Of Calcium Ion Regulation Of Cilium Assembly Regulation Of Organelle Assembly Calcium Channel Complex Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Calcium Ion Transmembrane Transport Calcineurin-mediated Signaling Myelin Sheath Negative Regulation Of Cell Population Proliferation Regulation Of Organelle Organization Thyrotropin-releasing Hormone Activity Positive Regulation Of Interleukin-17-mediated Signaling Pathway Negative Regulation Of Cilium Assembly Actin Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production
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