KISS1R

Description		KISS1 receptor
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GO Annotations	Cellular Component	Plasma Membrane Cilium Cell Surface Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Hormone Secretion
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		ANZ-100
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL) Precocious puberty, including: Central precocious puberty (CEPREPU); Familial male precocious puberty (FMPP)
GWAS		Menopause (age at onset) ( 26414677) Sweet taste preference ( 32572145)
Interacting Genes		3 interacting genes: KISS1 PPP2CA PTPA
Entrez ID		84634
HPRD ID		09167
Ensembl ID		ENSG00000116014
Uniprot IDs		Q969F8
PDB IDs		7YQE 8XGO 8XGS 8XGU 8ZJD 8ZJE
Enriched GO Terms of Interacting Partners?		Protein Phosphatase Type 2A Complex Kisspeptin Receptor Binding RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Phosphoprotein Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Luteinizing Hormone Secretion Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Protein Tyrosine Phosphatase Activator Activity Phosphatase Activator Activity Protein Serine/threonine Phosphatase Complex Peptidyl-threonine Dephosphorylation ATPase Complex INTAC Complex Vascular Endothelial Cell Response To Fluid Shear Stress GABA Receptor Binding FAR/SIN/STRIPAK Complex Negative Regulation Of Glycolytic Process Response To Lead Ion RNA Polymerase II Transcription Initiation Surveillance Negative Regulation Of Hippo Signaling Negative Regulation Of ATP Metabolic Process Calcium Channel Complex Protein Phosphatase 2A Binding Positive Regulation Of NLRP3 Inflammasome Complex Assembly Cellular Response To Fluid Shear Stress T Cell Homeostasis Peptidyl-prolyl Cis-trans Isomerase Activity Nuclear RNA Surveillance RNA Surveillance Protein Phosphatase Regulator Activity Regulation Of Hippo Signaling Transcription Elongation By RNA Polymerase II Response To Fluid Shear Stress Negative Regulation Of Epithelial To Mesenchymal Transition Tau Protein Binding Regulation Of NLRP3 Inflammasome Complex Assembly Cytoskeleton Organization Regulation Of Glycolytic Process DNA-templated Transcription Elongation Phosphatase Binding Mesoderm Development Lymphocyte Homeostasis Regulation Of Microtubule Polymerization Regulation Of Carbohydrate Catabolic Process
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