MOB1A and MST1

Number of citations of the paper that reports this interaction (PMID 17347649)
54

Data Source:
HPRD (in vivo)

		MOB1A	MST1
Gene Name		MOB kinase activator 1A	macrophage stimulating 1 (hepatocyte growth factor-like)
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Metal Ion Binding	Molecular_function Serine-type Endopeptidase Activity
	Biological Process	Hippo Signaling	Proteolysis Spermatogenesis Embryo Implantation Biological_process Sperm Motility
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS			Crohn's disease ( 18587394 17554261 17554300 21102463) Inflammatory bowel disease ( 23128233) Primary sclerosing cholangitis ( 21151127) Ulcerative colitis ( 19915572 20228799 21297633)
Protein-Protein Interactions		11 interactors: APP CCDC85B CMTM3 FAM118A FAM9B KANK2 KXD1 MST1 SEPT3 STRN3 TDO2	8 interactors: DAXX FOXO1 HIST2H2BE KLKB1 MOB1A MST1R RASSF1 SERPINA3
Entrez ID		55233	4485
HPRD ID		14727	00798
Ensembl ID			ENSG00000173531
Uniprot IDs		Q9H8S9	G3XAK1 P26927 Q53GN8
PDB IDs		1PI1 4JIZ	2ASU
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Vitamin D Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Tryptophan Catabolic Process To Acetyl-CoA Regulation Of Fat Cell Differentiation Collateral Sprouting In Absence Of Injury Regulation Of Growth Regulation Of Protein Binding Regulation Of Signal Transduction Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Vitamin D Receptor Signaling Pathway Axon Choice Point Recognition Positive Regulation Of B Cell Receptor Signaling Pathway Regulation Of Signaling Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Neuron Remodeling Primitive Hemopoiesis Tryptophan Catabolic Process To Kynurenine Negative Regulation Of Growth	Response To Stress Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Defense Response Response To Stimulus Acute Inflammatory Response Factor XII Activation Nucleosome Assembly Chromatin Assembly Regulation Of MAPK Cascade Macrophage Colony-stimulating Factor Signaling Pathway Nucleosome Organization Chromatin Assembly Or Disassembly Positive Regulation Of Fibrinolysis Protein-DNA Complex Assembly DNA Packaging Regulation Of Stress-activated MAPK Cascade Innate Immune Response Regulation Of Protein Ubiquitination Intracellular Signal Transduction Positive Regulation Of MAP Kinase Activity Cellular Response To Cold Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To Macrophage Colony-stimulating Factor Stimulus Multicellular Organismal Homeostasis Positive Regulation Of Protein Modification Process Plasminogen Activation Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hyperoxia Plasma Kallikrein-kinin Cascade Positive Regulation Of Protein Serine/threonine Kinase Activity DNA Conformation Change Regulation Of Energy Homeostasis Regulation Of MAP Kinase Activity Cellular Response To Nitric Oxide Regulation Of Fibrinolysis Positive Regulation Of Cellular Protein Metabolic Process Blood Coagulation, Intrinsic Pathway Maintenance Of Gastrointestinal Epithelium Response To Nitric Oxide Innate Immune Response In Mucosa Positive Regulation Of Gluconeogenesis Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Processing Epithelial Structure Maintenance Immune Response Regulation Of Phosphorylation Regulation Of Protein Processing Cellular Response To Reactive Nitrogen Species
Tagcloud ?		agc canonical closest compensate discoveries emphasis ensures flies hippo inactivates lats lats1 mammals mats metazoan module mst1 mst2 ndr ndr1 ordinating phosphorylates relatives ste20 taz yap yorkie	ac acetylcysteine antioxidants asp budding caspases ch2 cho cytotrienin dcb devd h2o2 hl immunologically krs1 krs2 mbp mst2 myelin okadaic originally p36 peroxide programmed proteases ste20 streptomyces virtue yvad
Tagcloud (Difference) ?		agc canonical closest compensate discoveries emphasis ensures flies hippo inactivates lats lats1 mammals mats metazoan module ndr ndr1 ordinating phosphorylates relatives taz yap yorkie	ac acetylcysteine antioxidants asp budding caspases ch2 cho cytotrienin dcb devd h2o2 hl immunologically krs1 krs2 mbp myelin okadaic originally p36 peroxide programmed proteases streptomyces virtue yvad
Tagcloud (Intersection) ?		mst1 mst2 ste20