MOB1A and STRN3

Number of citations of the paper that reports this interaction (PubMedID 11319234)
43

Data Source:
HPRD (in vivo)

		MOB1A	STRN3
Description		MOB kinase activator 1A	striatin 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Membrane Dendrite Protein-containing Complex Neuronal Cell Body FAR/SIN/STRIPAK Complex Postsynapse
	Molecular Function	Protein Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity Metal Ion Binding	Protein Binding Calmodulin Binding Protein-macromolecule Adaptor Activity Small GTPase Binding Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Hippo Signaling	Negative Regulation Of Transcription By RNA Polymerase II Response To Estradiol Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Hippo Signaling Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 32888494) Platelet count ( 32888494)
Interacting Genes		22 interacting genes: APP CCDC85B CMTM3 CREBBP FAM118A FAM9B GMEB2 HDAC6 IKZF4 KANK2 KXD1 LZTFL1 MST1 PCYT1A PTPN5 SEPTIN3 STRN3 TDO2 TMEM190 TRIM32 WASHC3 WEE2-AS1	10 interacting genes: CALM1 GABARAPL1 MOB1A NR3C1 PPP2R1A PPP2R1B PPP2R2A SIKE1 SLC2A4 TCEANC
Entrez ID		55233	29966
HPRD ID		14727	11613
Ensembl ID		ENSG00000114978	ENSG00000196792
Uniprot IDs		Q9H8S9	Q13033
PDB IDs		1PI1 4J1V 4JIZ 5BRK 5BRM 5TWF 5TWG 5TWH 5XQZ 6MCP 6MCQ	4N6J 6AKL 6IUR 7K36
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Estrogen Receptor Signaling Pathway	Protein Phosphatase Type 2A Complex Protein Phosphatase Regulator Activity Meiotic Sister Chromatid Cohesion, Centromeric Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Meiotic Sister Chromatid Cohesion FAR/SIN/STRIPAK Complex Negative Regulation Of Hippo Signaling Cytosol Sister Chromatid Cohesion Regulation Of Hippo Signaling Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Nuclear Glucocorticoid Receptor Activity Meiotic Spindle Elongation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Protein Serine/threonine Kinase Activator Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Meiotic Cell Cycle Process Involved In Oocyte Maturation Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Spindle Assembly Protein Kinase Binding Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Positive Regulation Of Programmed Cell Death Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Chromosome Segregation Positive Regulation Of Apoptotic Process Nuclear Receptor-mediated Corticosteroid Signaling Pathway Steroid Hormone Binding Positive Regulation Of Apoptotic Signaling Pathway Mitotic Sister Chromatid Separation Spindle Elongation Insulin-responsive Compartment Glucose Import In Response To Insulin Stimulus White Fat Cell Proliferation Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Autophagosome Membrane Docking Response To Cortisol Spindle Organization Regulation Of Extrinsic Apoptotic Signaling Pathway Vesicle Negative Regulation Of Voltage-gated Calcium Channel Activity
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