MST1 and MOB1A

Number of citations of the paper that reports this interaction (PMID 17347649)
54

Data Source:
HPRD (in vivo)

		MST1	MOB1A
Gene Name		macrophage stimulating 1 (hepatocyte growth factor-like)	MOB kinase activator 1A
Image
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Serine-type Endopeptidase Activity	Protein Binding Metal Ion Binding
	Biological Process	Proteolysis Spermatogenesis Embryo Implantation Biological_process Sperm Motility	Hippo Signaling
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Crohn's disease ( 18587394 17554261 17554300 21102463) Inflammatory bowel disease ( 23128233) Primary sclerosing cholangitis ( 21151127) Ulcerative colitis ( 19915572 20228799 21297633)
Protein-Protein Interactions		8 interactors: DAXX FOXO1 HIST2H2BE KLKB1 MOB1A MST1R RASSF1 SERPINA3	11 interactors: APP CCDC85B CMTM3 FAM118A FAM9B KANK2 KXD1 MST1 SEPT3 STRN3 TDO2
Entrez ID		4485	55233
HPRD ID		00798	14727
Ensembl ID		ENSG00000173531
Uniprot IDs		G3XAK1 P26927 Q53GN8	Q9H8S9
PDB IDs		2ASU	1PI1 4JIZ
Enriched GO Terms of Interacting Partners?		Response To Stress Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Defense Response Response To Stimulus Acute Inflammatory Response Factor XII Activation Nucleosome Assembly Chromatin Assembly Regulation Of MAPK Cascade Macrophage Colony-stimulating Factor Signaling Pathway Nucleosome Organization Chromatin Assembly Or Disassembly Positive Regulation Of Fibrinolysis Protein-DNA Complex Assembly DNA Packaging Regulation Of Stress-activated MAPK Cascade Innate Immune Response Regulation Of Protein Ubiquitination Intracellular Signal Transduction Positive Regulation Of MAP Kinase Activity Cellular Response To Cold Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To Macrophage Colony-stimulating Factor Stimulus Multicellular Organismal Homeostasis Positive Regulation Of Protein Modification Process Plasminogen Activation Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hyperoxia Plasma Kallikrein-kinin Cascade Positive Regulation Of Protein Serine/threonine Kinase Activity DNA Conformation Change Regulation Of Energy Homeostasis Regulation Of MAP Kinase Activity Cellular Response To Nitric Oxide Regulation Of Fibrinolysis Positive Regulation Of Cellular Protein Metabolic Process Blood Coagulation, Intrinsic Pathway Maintenance Of Gastrointestinal Epithelium Response To Nitric Oxide Innate Immune Response In Mucosa Positive Regulation Of Gluconeogenesis Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Processing Epithelial Structure Maintenance Immune Response Regulation Of Phosphorylation Regulation Of Protein Processing Cellular Response To Reactive Nitrogen Species	Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Vitamin D Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Tryptophan Catabolic Process To Acetyl-CoA Regulation Of Fat Cell Differentiation Collateral Sprouting In Absence Of Injury Regulation Of Growth Regulation Of Protein Binding Regulation Of Signal Transduction Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Vitamin D Receptor Signaling Pathway Axon Choice Point Recognition Positive Regulation Of B Cell Receptor Signaling Pathway Regulation Of Signaling Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Neuron Remodeling Primitive Hemopoiesis Tryptophan Catabolic Process To Kynurenine Negative Regulation Of Growth
Tagcloud ?		ac acetylcysteine antioxidants asp budding caspases ch2 cho cytotrienin dcb devd h2o2 hl immunologically krs1 krs2 mbp mst2 myelin okadaic originally p36 peroxide programmed proteases ste20 streptomyces virtue yvad	agc canonical closest compensate discoveries emphasis ensures flies hippo inactivates lats lats1 mammals mats metazoan module mst1 mst2 ndr ndr1 ordinating phosphorylates relatives ste20 taz yap yorkie
Tagcloud (Difference) ?		ac acetylcysteine antioxidants asp budding caspases ch2 cho cytotrienin dcb devd h2o2 hl immunologically krs1 krs2 mbp myelin okadaic originally p36 peroxide programmed proteases streptomyces virtue yvad	agc canonical closest compensate discoveries emphasis ensures flies hippo inactivates lats lats1 mammals mats metazoan module ndr ndr1 ordinating phosphorylates relatives taz yap yorkie
Tagcloud (Intersection) ?		mst1 mst2 ste20