MOB1A and GMEB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MOB1A	GMEB2
Description		MOB kinase activator 1A	glucocorticoid modulatory element binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Hippo Signaling	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Prostate cancer ( 23535732) Refractive error ( 32231278) Reticulocyte count ( 32888494)
Interacting Genes		22 interacting genes: APP CCDC85B CMTM3 CREBBP FAM118A FAM9B GMEB2 HDAC6 IKZF4 KANK2 KXD1 LZTFL1 MST1 PCYT1A PTPN5 SEPTIN3 STRN3 TDO2 TMEM190 TRIM32 WASHC3 WEE2-AS1	20 interacting genes: ATXN1 ATXN1L CBFA2T3 CDC7 CEP19 CREBBP FHL2 GMEB1 LMO2 LMO3 MAP1LC3C MOB1A MXRA8 PIN1 POGZ POU6F2 TRAF3 TTF2 UBE2I ZMYND19
Entrez ID		55233	26205
HPRD ID		14727	16245
Ensembl ID		ENSG00000114978	ENSG00000101216
Uniprot IDs		Q9H8S9	B4DQS0 Q9UKD1
PDB IDs		1PI1 4J1V 4JIZ 5BRK 5BRM 5TWF 5TWG 5TWH 5XQZ 6MCP 6MCQ
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Estrogen Receptor Signaling Pathway	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process POZ Domain Binding Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Nucleus Metal Ion Binding Cytoplasm Transcription Factor Binding Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Transcription By RNA Polymerase II BHLH Transcription Factor Binding Postsynaptic Cytosol Recombinational Repair Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Transcription Coregulator Binding Cis-trans Isomerase Activity SUMO Conjugating Enzyme Activity Hsp27 Protein Binding Establishment Of Glial Blood-brain Barrier Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment DNA-binding Transcription Factor Binding Tau Protein Binding Lung Alveolus Development DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Transcription Corepressor Activity Social Behavior Histone H3K27 Acetyltransferase Activity Atrial Cardiac Muscle Cell Development Susceptibility To T Cell Mediated Cytotoxicity Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Double-strand Break Repair Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Metabolic Process DNA Recombination Negative Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation DNA Repair Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
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