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PPP2CB and C22orf39
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
PPP2CB
C22orf39
Description
protein phosphatase 2 catalytic subunit beta
chromosome 22 open reading frame 39
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Protein Phosphatase Type 2A Complex
Chromosome, Centromeric Region
Spindle Pole
Nucleus
Chromosome
Cytoplasm
Cytosol
Cytoskeleton
FAR/SIN/STRIPAK Complex
Extracellular Region
Mitochondrion
Synaptic Cleft
Synapse
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Serine/threonine Phosphatase Activity
Protein Binding
Hydrolase Activity
Transmembrane Transporter Binding
Metal Ion Binding
Tau Protein Binding
Protein Binding
Biological Process
Mitotic Cell Cycle
Protein Dephosphorylation
Apoptotic Mitochondrial Changes
Response To Lead Ion
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of Microtubule Polymerization
Response To Endoplasmic Reticulum Stress
Response To Hydrogen Peroxide
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Ras Protein Signal Transduction
Response To Antibiotic
Regulation Of Neurofibrillary Tangle Assembly
Regulation Of Synaptic Plasticity
Negative Regulation Of Long-term Synaptic Potentiation
Pathways
Inhibition of replication initiation of damaged DNA by RB1/E2F1
Spry regulation of FGF signaling
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
PP2A-mediated dephosphorylation of key metabolic factors
DARPP-32 events
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
ERK/MAPK targets
ERKs are inactivated
MASTL Facilitates Mitotic Progression
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Co-stimulation by CD28
Co-inhibition by CTLA4
Platelet sensitization by LDL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Signaling by GSK3beta mutants
CTNNB1 S33 mutants aren't phosphorylated
CTNNB1 S37 mutants aren't phosphorylated
CTNNB1 S45 mutants aren't phosphorylated
CTNNB1 T41 mutants aren't phosphorylated
APC truncation mutants have impaired AXIN binding
AXIN missense mutants destabilize the destruction complex
Truncations of AMER1 destabilize the destruction complex
RHO GTPases Activate Formins
RAF activation
Negative regulation of MAPK pathway
Regulation of TP53 Degradation
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Mitotic Prometaphase
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
EML4 and NUDC in mitotic spindle formation
PKR-mediated signaling
Drugs
Vitamin E
Diseases
GWAS
Daytime sleep phenotypes (
27126917
)
Heel bone mineral density x serum urate levels interaction (
34046847
)
Interacting Genes
41 interacting genes:
ACP5
AXIN1
BHLHE41
BUB1
C22orf39
DOCK7
DYNLT2B
EGFR
GAD1
GSTA1
HK3
KRAS
LCMT1
MAK
MAPT
MID1
MLH1
MLH3
NRAS
PACS1
PDGFRL
PLXNA3
PMS2
PRKCB
PTPRJ
RAF1
RELA
RPLP1
SGO1
SMAD4
SRC
STK11
TAB1
TAB2
TGFBR2
TIPRL
TLX1
TRMT61B
UBC
ZFP28
ZNF775
42 interacting genes:
ANKS1A
BANP
CABP2
CEP76
COL8A1
CRYBA2
CYSRT1
DTX2
EXOSC8
FRS3
GNE
GRN
HSD3B7
ID2
ID3
INCA1
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP13-2
KRTAP9-2
MAGEA11
MAPK8IP2
MDFI
MGAT5B
NFATC2IP
PCSK5
PFDN5
PLSCR3
PPP2CB
PSMA1
RBPMS
RECK
RIMBP3C
SNX32
SYCE1L
TRIB3
VWC2L
ZNF620
Entrez ID
5516
128977
HPRD ID
01487
14041
Ensembl ID
ENSG00000104695
ENSG00000242259
Uniprot IDs
A0A140VJS0
P62714
Q6P5X5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Intracellular Signal Transduction
Mismatch Repair Complex
Cellular Response To Growth Factor Stimulus
Enzyme-linked Receptor Protein Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Signal Transduction
Response To Growth Factor
MAPK Cascade
Kinase Activity
Mismatched DNA Binding
Regulation Of Protein Modification Process
Cell Surface Receptor Signaling Pathway
Protein Kinase Activity
Positive Regulation Of Signal Transduction
Enzyme Binding
Chiasma
Intracellular Signaling Cassette
Positive Regulation Of Multicellular Organismal Process
Cytosol
Regulation Of Multicellular Organismal Process
ATP-dependent DNA Damage Sensor Activity
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of MAPK Cascade
MutLalpha Complex
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Signal Transduction
ERBB2 Signaling Pathway
Positive Regulation Of Protein Phosphorylation
ATP Binding
Immune Response-activating Signaling Pathway
Regulation Of Neurogenesis
Regulation Of MAPK Cascade
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Phosphorylation
Morphogenesis Of A Branching Epithelium
Positive Regulation Of Immune Response
Positive Regulation Of Protein Modification Process
Animal Organ Morphogenesis
Anatomical Structure Morphogenesis
Regulation Of Protein Phosphorylation
Regulation Of Developmental Process
Phosphorylation
Gland Morphogenesis
Morphogenesis Of A Branching Structure
Mismatch Repair
Cell Development
Nucleotide Binding
Negative Regulation Of Cellular Component Organization
Transferase Activity
Keratin Filament
Intermediate Filament
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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