RIMBP3 and DTX2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RIMBP3	DTX2
Gene Name		RIMS binding protein 3	deltex 2, E3 ubiquitin ligase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function		Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process		Notch Signaling Pathway Protein Ubiquitination
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		18 interactors: AES AQP1 ARNT2 CATSPER1 CREB5 CTBP2 DGCR6 DGCR6L DTX2 FANCL MVP NOXA1 POLR1C PPIL1 PRKAA1 PRKAB2 TRAF3IP2 ZNF488	41 interactors: ABHD16A ALKBH4 ARNT2 C1orf94 DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS RBPMS RFX6 RHOXF2 RIMBP3 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1
Entrez ID		85376	113878
HPRD ID		13881	16841
Ensembl ID		ENSG00000196622	ENSG00000091073
Uniprot IDs		Q9UFD9	Q86UW9
PDB IDs		2EGE
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Ammonium Transmembrane Transport Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation RNA Metabolic Process Cellular Response To Hydrogen Peroxide Response To Hypoxia Ammonium Transport Gene Expression Carbon Dioxide Transmembrane Transport Corticotropin Secretion Establishment Or Maintenance Of Actin Cytoskeleton Polarity Nitrogen Compound Metabolic Process Metanephric Proximal Convoluted Tubule Development Nitric Oxide Transport Negative Regulation Of Glucose Import In Response To Insulin Stimulus Cellular Response To Mercury Ion Cellular Response To Hypoxia Negative Regulation Of Cellular Metabolic Process Cellular Response To Decreased Oxygen Levels Cellular Response To Reactive Oxygen Species Biosynthetic Process Response To Camptothecin Metanephric Proximal Tubule Development Positive Regulation Of Anoikis Cellular Response To Oxygen Levels Regulation Of Cell Proliferation Renal Water Absorption Positive Regulation Of Saliva Secretion Carbon Dioxide Transport Epithelial Fluid Transport Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Fat Cell Differentiation Response To Hydrogen Peroxide Response To Hormone Fatty Acid Biosynthetic Process Response To UV Cellular Response To Organonitrogen Compound Positive Regulation Of Chromatin Binding Renal Water Transport	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K48-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transcription, DNA-templated RNA Biosynthetic Process Protein Modification By Small Protein Conjugation Transcription From RNA Polymerase II Promoter Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Innate Immune Response Protein K11-linked Ubiquitination RNA Metabolic Process Cellular Response To Oxygen Levels Heart Trabecula Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Hypoxia Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Notch Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Cellular Response To Stimulus Cellular Nitrogen Compound Metabolic Process Pancreatic Epsilon Cell Differentiation Glutaminyl-tRNA Aminoacylation Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Pancreatic D Cell Differentiation Cleavage Furrow Ingression Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Protein Polyubiquitination Glandular Epithelial Cell Differentiation Signal Transduction Trabecula Morphogenesis Positive Regulation Of Innate Immune Response Vesicle Fusion Regulation Of Immune System Process Prolyl-tRNA Aminoacylation Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Histamine Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?			algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Difference) ?			algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Intersection) ?