AVP and TXNDC17

Number of citations of the paper that reports this interaction (PMID 14607844)
12

Data Source:
HPRD (in vitro)

		AVP	TXNDC17
Gene Name		arginine vasopressin	thioredoxin domain containing 17
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Secretory Granule Dendrite	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase Activity Signal Transducer Activity Receptor Binding Neuropeptide Hormone Activity Neurohypophyseal Hormone Activity V1A Vasopressin Receptor Binding V1B Vasopressin Receptor Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process	Peroxidase Activity Protein Binding Electron Carrier Activity Protein-disulfide Reductase Activity
	Biological Process	Maternal Aggressive Behavior Positive Regulation Of Systemic Arterial Blood Pressure Renal Water Homeostasis Generation Of Precursor Metabolites And Energy Protein Phosphorylation Water Transport Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Negative Regulation Of Female Receptivity Circadian Rhythm Grooming Behavior Locomotory Behavior Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Glutamate Secretion Positive Regulation Of Cell Growth Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of Prostaglandin Biosynthetic Process Positive Regulation Of Cellular PH Reduction Positive Regulation Of Peptidyl-serine Phosphorylation Response To Testosterone Response To Nicotine Social Behavior Regulation Of Renal Sodium Excretion Vasoconstriction Hyperosmotic Salinity Response Maternal Behavior Negative Regulation Of Apoptotic Process Penile Erection Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Sodium-independent Organic Anion Transport Response To Ethanol Positive Regulation Of Vasoconstriction Negative Regulation Of Transmission Of Nerve Impulse Transmembrane Transport ERK1 And ERK2 Cascade Protein Kinase C Signaling Negative Regulation Of Release Of Cytochrome C From Mitochondria	Tumor Necrosis Factor-mediated Signaling Pathway Oxidation-reduction Process
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events Signaling by GPCR Vasopressin-like receptors G alpha (s) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding Aquaporin-mediated transport SLC-mediated transmembrane transport Transport of organic anions G alpha (q) signalling events GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Transport of vitamins, nucleosides, and related molecules BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AVPR1A AVPR1B AVPR2 CRYAB DLX2 KMT2A OXTR TXNDC17	8 interactors: AVP DYNLL1 EXOSC8 INS OXT RUFY1 TINF2 TXNRD1
Entrez ID		551	84817
HPRD ID		01891	11656
Ensembl ID		ENSG00000101200	ENSG00000129235
Uniprot IDs		P01185	Q9BRA2
PDB IDs			1WOU
Enriched GO Terms of Interacting Partners?		Regulation Of Systemic Arterial Blood Pressure By Vasopressin Positive Regulation Of Vasoconstriction Regulation Of Vasoconstriction Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Blood Pressure Regulation Of Blood Pressure Telencephalon Development Sperm Ejaculation Blood Circulation Response To Hormone Positive Regulation Of Systemic Arterial Blood Pressure Forebrain Development Maternal Behavior Response To Peptide Insemination Positive Regulation Of Cytosolic Calcium Ion Concentration Copulation Regulation Of Renal Sodium Excretion Cellular Response To Hormone Stimulus Cytosolic Calcium Ion Homeostasis Regulation Of Excretion Response To Organic Substance Brain Development Social Behavior Head Development Organ Development Response To Organonitrogen Compound Cellular Calcium Ion Homeostasis Chemical Homeostasis Calcium Ion Homeostasis Activation Of Phospholipase C Activity Mating Cellular Response To Organic Substance Positive Regulation Of Phospholipase C Activity Central Nervous System Development Negative Regulation Of Transport Cellular Metal Ion Homeostasis Positive Regulation Of Phospholipase Activity Cellular Cation Homeostasis G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cellular Response To Drug Cellular Ion Homeostasis Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Metal Ion Homeostasis Response To Steroid Hormone Cellular Chemical Homeostasis System Development Homeostatic Process Response To Estradiol	Maternal Aggressive Behavior Hyperosmotic Salinity Response Aggressive Behavior Regulation Of Cellular Component Organization Regulation Of Female Receptivity Maternal Behavior Female Mating Behavior Grooming Behavior Regulation Of Renal Sodium Excretion Copulation Hyperosmotic Response Regulation Of Excretion Homeostatic Process Mating Behavior Positive Regulation Of Transport Response To Salt Stress Positive Regulation Of Blood Pressure Social Behavior Positive Regulation Of Secretion Mating Regulation Of Organelle Organization Regulation Of Neurological System Process Positive Regulation Of Lipid Biosynthetic Process Regulation Of Cellular Localization Positive Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Hindgut Contraction Regulation Of Fatty Acid Metabolic Process Response To Osmotic Stress Regulation Of Mitochondrion Organization Renal System Process Regulation Of Protein ADP-ribosylation Negative Regulation Of Glycogen Catabolic Process Regulation Of Hindgut Contraction Ion Homeostasis Positive Regulation Of Cell Growth Regulation Of DNA Replication Regulation Of Lipid Biosynthetic Process Regulation Of Anion Transport Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Negative Regulation Of NAD(P)H Oxidase Activity Regulation Of Secretion Positive Regulation Of DNA Metabolic Process Response To Alkaloid Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Cellular Homeostasis Regulation Of Ion Homeostasis Positive Regulation Of Cellular PH Reduction Positive Regulation Of Norepinephrine Secretion
Tagcloud ?		arginine ascending bath ca2 camp car ctal fluxes henle hypotonic isotonic limb lumen medullary mg2 mmol mol mtal nacl net pdte perfusion phospholipase reabsorption segments sensing thick transepithelial vasopressin
Tagcloud (Difference) ?		arginine ascending bath ca2 camp car ctal fluxes henle hypotonic isotonic limb lumen medullary mg2 mmol mol mtal nacl net pdte perfusion phospholipase reabsorption segments sensing thick transepithelial vasopressin
Tagcloud (Intersection) ?