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PPP1R3A and RPS6KA1
Number of citations of the paper that reports this interaction (PMID
10648825
)
9
Data Source:
HPRD
(in vivo, in vitro)
PPP1R3A
RPS6KA1
Gene Name
protein phosphatase 1, regulatory subunit 3A
ribosomal protein S6 kinase, 90kDa, polypeptide 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Membrane
Nucleus
Nucleoplasm
Cytoplasm
Spindle
Cytosol
Molecular Function
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Biological Process
Glycogen Metabolic Process
Toll-like Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Protein Phosphorylation
Cell Cycle
Signal Transduction
Synaptic Transmission
Axon Guidance
Positive Regulation Of Cell Growth
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Translation In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Innate Immune Response
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Neurotrophin TRK Receptor Signaling Pathway
Stress-activated MAPK Cascade
Positive Regulation Of Hepatic Stellate Cell Activation
Pathways
Signaling by GPCR
CREB phosphorylation
Axon guidance
Toll Like Receptor 7/8 (TLR7/8) Cascade
Cellular Senescence
CREB phosphorylation
L1CAM interactions
Recycling pathway of L1
CREB phosphorylation through the activation of Ras
Toll Like Receptor TLR6:TLR2 Cascade
Toll Like Receptor TLR1:TLR2 Cascade
Activated TLR4 signalling
MyD88 cascade initiated on plasma membrane
Toll Like Receptor 5 (TLR5) Cascade
Gastrin-CREB signalling pathway via PKC and MAPK
RSK activation
Activation of NMDA receptor upon glutamate binding and postsynaptic events
MyD88 dependent cascade initiated on endosome
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
MyD88:Mal cascade initiated on plasma membrane
Toll Like Receptor 9 (TLR9) Cascade
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ERK/MAPK targets
Post NMDA receptor activation events
Innate Immune System
Signalling by NGF
MAP kinase activation in TLR cascade
TRIF-mediated TLR3/TLR4 signaling
Senescence-Associated Secretory Phenotype (SASP)
NGF signalling via TRKA from the plasma membrane
MyD88-independent cascade
Toll Like Receptor 2 (TLR2) Cascade
Toll-Like Receptors Cascades
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 4 (TLR4) Cascade
ERK/MAPK targets
Toll Like Receptor 3 (TLR3) Cascade
MAPK targets/ Nuclear events mediated by MAP kinases
Transmission across Chemical Synapses
Nuclear Events (kinase and transcription factor activation)
Drugs
Diseases
GWAS
Protein-Protein Interactions
2 interactors:
PLN
RPS6KA1
51 interactors:
ATXN3
BAD
CARHSP1
CCT4
CDKN1B
CEBPB
CFL1
CREB1
CREBBP
DDAH2
DLC1
EEF1D
EEF2K
ESR1
ETV1
FGFR1
FOS
GBP2
GMFB
GRB2
GSK3B
L1CAM
MAGI1
MAPK1
MAPK3
MAPT
METTL1
MITF
MPP1
MTOR
MXD1
NFKBIA
NR4A1
NR4A2
NR4A3
PDCD4
PDPK1
PHAX
POLDIP3
PPM1G
PPP1R3A
RPTOR
SRF
SRSF5
SYK
TOB2
TSC2
TTK
VCP
YBX1
YWHAB
Entrez ID
5506
6195
HPRD ID
02950
03402
Ensembl ID
ENSG00000154415
ENSG00000117676
Uniprot IDs
Q16821
E9PRI4
Q15418
PDB IDs
2WNT
2Z7Q
2Z7R
2Z7S
3RNY
3TEI
4H3P
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Calcium-transporting ATPase Activity
Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Negative Regulation Of Calcium Ion Binding
Positive Regulation Of Hepatic Stellate Cell Activation
Regulation Of The Force Of Heart Contraction By Cardiac Conduction
Regulation Of Calcium-transporting ATPase Activity
Adrenergic Receptor Signaling Pathway Involved In Heart Process
Negative Regulation Of Hydrolase Activity
G-protein Coupled Receptor Signaling Pathway Involved In Heart Process
Negative Regulation Of Calcium Ion Import
Regulation Of Relaxation Of Cardiac Muscle
Negative Regulation Of ATPase Activity
Regulation Of Cardiac Muscle Cell Membrane Potential
Regulation Of Relaxation Of Muscle
Negative Regulation Of Heart Rate
Relaxation Of Cardiac Muscle
Negative Regulation Of Catalytic Activity
Adrenergic Receptor Signaling Pathway
Regulation Of Translation In Response To Stress
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Relaxation Of Muscle
Regulation Of Calcium Ion Import
Negative Regulation Of Heart Contraction
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of The Force Of Heart Contraction
Response To Testosterone
Negative Regulation Of Transporter Activity
Regulation Of ATPase Activity
Negative Regulation Of Calcium Ion Transport
Regulation Of Cardiac Muscle Cell Contraction
Cardiac Conduction
Negative Regulation Of Ion Transmembrane Transport
Response To Zinc Ion
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Negative Regulation Of Transmembrane Transport
Regulation Of DNA-templated Transcription In Response To Stress
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Calcium Ion Transmembrane Transport
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Fc Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Fibroblast Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Neurotrophin Signaling Pathway
Immune Response-regulating Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Innate Immune Response
Response To Fibroblast Growth Factor
Response To Organonitrogen Compound
Cellular Response To Organic Substance
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Metabolic Process
Response To Organic Substance
Enzyme Linked Receptor Protein Signaling Pathway
Response To Hormone
Cellular Response To Growth Factor Stimulus
Regulation Of Immune System Process
Immune Response
Response To Growth Factor
Regulation Of Immune Response
Defense Response
Positive Regulation Of Cellular Biosynthetic Process
Response To Abiotic Stimulus
Phosphatidylinositol-mediated Signaling
Response To External Stimulus
Cellular Response To Hormone Stimulus
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Insulin Receptor Signaling Pathway
Response To Peptide
Cellular Response To Heat
Immune System Process
Cell Communication
Regulation Of Phosphorylation
Response To Temperature Stimulus
Response To Peptide Hormone
Positive Regulation Of Transcription, DNA-templated
Signal Transduction
Signaling
Positive Regulation Of Gene Expression
Response To Stress
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Chemotaxis
Cellular Response To Insulin Stimulus
Tagcloud
?
alkenes
azotic
constructions
gnai1
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkcd
prkce
prkcg
prkd1
propertied
pubchem
rock2
tlr8
tradition
Tagcloud (Difference)
?
alkenes
azotic
constructions
gnai1
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkcd
prkce
prkcg
prkd1
propertied
pubchem
rock2
tlr8
tradition
Tagcloud (Intersection)
?