PPP1R3A and PPP1CB

Number of citations of the paper that reports this interaction (PubMedID 15016827)
0

Data Source:
BioGRID (far western blotting)

		PPP1R3A	PPP1CB
Description		protein phosphatase 1 regulatory subunit 3A	protein phosphatase 1 catalytic subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Membrane	Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Focal Adhesion Extracellular Exosome PTW/PP1 Phosphatase Complex
	Molecular Function	Protein Phosphatase 1 Binding Glycogen Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Hydrolase Activity Phosphatase Activity Myosin Phosphatase Activity Protein Kinase Binding Metal Ion Binding Myosin-light-chain-phosphatase Activity
	Biological Process	Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process	MAPK Cascade Glycogen Metabolic Process Protein Dephosphorylation Regulation Of Cell Adhesion Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Rhythmic Process Cell Division
Pathways			Triglyceride catabolism Downregulation of TGF-beta receptor signaling Regulation of PLK1 Activity at G2/M Transition RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs RAF activation SHOC2 M1731 mutant abolishes MRAS complex function Gain-of-function MRAS complexes activate RAF signaling Maturation of hRSV A proteins Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood pressure (smoking interaction) ( 25189868) Chronotype ( 30696823) Hand grip strength ( 29691431) Schizophrenia ( 28991256 30285260) Walking pace ( 33128006)	Body mass index ( 25673413) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Excessive sweating ( 29895819) Heel bone mineral density ( 28869591 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) Pure non-grapefruit juice consumption ( 31046077)
Interacting Genes		8 interacting genes: PLN PPP1CB PPP1CC PPP1R11 PPP1R7 RPS6KA1 UBXN2B VCP	46 interacting genes: ACTN2 AURKA BRCA1 C14orf180 CHCHD3 CLK1 CLOCK CSNK2B CSRNP2 CYSRT1 DELEC1 FBXO7 H3-3A H3C1 HOXA2 KANK2 KIF23 LMTK2 MAPT MEOX2 NONO PHACTR3 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R16A PPP1R27 PPP1R2B PPP1R2C PPP1R3A PPP1R3B PPP1R3C PPP1R7 PPP1R9A PPP2R5C PRKAR2A PTK2 RB1 RORC SPATC1L TLX1 TP53BP2 UBAC1 WBP11 ZFYVE9
Entrez ID		5506	5500
HPRD ID		02950	11792
Ensembl ID		ENSG00000154415	ENSG00000213639
Uniprot IDs		Q16821	P62140 V9HW04
PDB IDs		5ZQV
Enriched GO Terms of Interacting Partners?		PTW/PP1 Phosphatase Complex Circadian Rhythm Photoperiodism Entrainment Of Circadian Clock Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Rhythmic Process Intracellular Signaling Cassette Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Intracellular Signal Transduction Response To Light Stimulus Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Glycogen Metabolic Process Protein Modification Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Circadian Regulation Of Gene Expression Phosphatase Activity Protein Metabolic Process Myosin-light-chain-phosphatase Activity Flavin Adenine Dinucleotide Catabolic Process Regulation Of The Force Of Heart Contraction By Cardiac Conduction Calcium Ion-transporting ATPase Complex Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Response To Radiation Protein Serine/threonine Phosphatase Activity Protein Dephosphorylation Protein Phosphatase Binding VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Positive Regulation Of Protein K63-linked Deubiquitination Negative Regulation Of Protein Localization To Centrosome Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Regulation Of Circadian Rhythm Cellular Response To Arsenite Ion Mitotic Spindle Disassembly Positive Regulation Of Oxidative Phosphorylation Positive Regulation Of Mitotic Centrosome Separation Microtubule Cytoskeleton Organization Involved In Mitosis Circadian Sleep/wake Cycle Process Myosin Phosphatase Activity Phosphoprotein Phosphatase Activity Dephosphorylation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cytoplasm Protein Quality Control BAT3 Complex Binding Phosphate-containing Compound Metabolic Process ATPase Inhibitor Activity	Myosin Phosphatase Regulator Activity Protein Phosphatase Inhibitor Activity Phosphatase Regulator Activity Protein Phosphatase 1 Binding Glycogen Binding Protein Phosphatase Regulator Activity Protein Phosphatase Type 1 Complex Phosphatase Binding Enzyme Inhibitor Activity Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Regulation Of Glycogen Biosynthetic Process Stress Fiber Regulation Of Centromere Complex Assembly Regulation Of Glycogen Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Protein Kinase Binding Centrosome Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Chromatin Cell Projection Organization Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle A Band Segment Specification Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Cycle Process
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