ADPRS and FRA10AC1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ADPRS	FRA10AC1
Description		ADP-ribosylserine hydrolase	FRA10A associated CGG repeat 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Mitochondrion Mitochondrial Matrix Nuclear Body Site Of DNA Damage	Nucleus
	Molecular Function	Magnesium Ion Binding Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Poly(ADP-ribose) Glycohydrolase Activity Protein Binding Hydrolase Activity Metal Ion Binding O-acetyl-ADP-ribose Deacetylase Activity ADP-ribosylserine Hydrolase Activity	Protein Binding Phosphatase Activity
	Biological Process	DNA Repair Base-excision Repair, Gap-filling DNA Damage Response Negative Regulation Of Necroptotic Process Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation	MRNA Splicing, Via Spliceosome
Pathways		POLB-Dependent Long Patch Base Excision Repair
Drugs
Diseases
GWAS			Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: FRA10AC1 HEXD HSPB1 PRDM5 TNKS	27 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D GATD3 GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830
Entrez ID		54936	118924
HPRD ID		12432	12319
Ensembl ID		ENSG00000116863	ENSG00000148690
Uniprot IDs		B7ZAN4 Q9NX46	Q70Z53
PDB IDs		2FOZ 2FP0 2G4K 5ZQY 6D36 6D3A 7AKR 7AKS 7ARW 7L9F 7L9H 7L9I
Enriched GO Terms of Interacting Partners?			RNA Splicing MRNA Processing U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Nuclear Speck Spliceosomal Complex Nucleic Acid Metabolic Process RNA Metabolic Process Nucleoplasm RNA Binding Cajal Body Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome U2-type Spliceosomal Complex Glycerophosphoinositol Inositolphosphodiesterase Activity ADP-ribosylserine Hydrolase Activity Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation Nucleus Nucleic Acid Binding
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