FRA10AC1 and MOB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FRA10AC1	MOB2
Description		FRA10A associated CGG repeat 1	MOB kinase activator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phosphatase Activity	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Signal Transduction
Pathways
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)	Brain morphology (MOSTest) ( 32665545) Myocardial infarction ( 33532862) Prostate cancer ( 29892016) Refractive error ( 32231278)
Interacting Genes		27 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D GATD3 GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830	11 interacting genes: ATG3 CCDC90B FAAP20 FRA10AC1 MIIP NDRG2 NTAQ1 OR5H1 RETREG3 SFT2D2 STK38
Entrez ID		118924	81532
HPRD ID		12319	17581
Ensembl ID		ENSG00000148690	ENSG00000182208
Uniprot IDs		Q70Z53	Q70IA6
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Nuclear Speck Spliceosomal Complex Nucleic Acid Metabolic Process RNA Metabolic Process Nucleoplasm RNA Binding Cajal Body Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome U2-type Spliceosomal Complex Glycerophosphoinositol Inositolphosphodiesterase Activity ADP-ribosylserine Hydrolase Activity Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation Nucleus Nucleic Acid Binding
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