FRA10AC1 and VPS29

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FRA10AC1	VPS29
Gene Name		fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	vacuolar protein sorting 29 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Retromer Complex Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Protein Transporter Activity
	Biological Process		Intracellular Protein Transport Retrograde Transport, Endosome To Golgi Retrograde Transport, Endosome To Plasma Membrane
Pathways			WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 Signaling by Wnt Signaling by WNT in cancer WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ADPRHL2 C21orf33 C7orf25 CCDC155 CHERP CWC27 DGCR14 EEF1D GDPD2 GLRX3 HABP4 IK LPPR4 MAP3K12 MFAP1 NKAP PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830	5 interactors: APP FRA10AC1 RGS2 TBC1D5 VPS35
Entrez ID		118924	51699
HPRD ID		12319	09499
Ensembl ID		ENSG00000148690	ENSG00000111237
Uniprot IDs		Q70Z53	F8VXU5 Q9UBQ0
PDB IDs			1W24 2R17
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Chromosome Localization To Nuclear Envelope Involved In Synapsis Negative Regulation Of Isotype Switching To IgA Isotypes MRNA Export From Nucleus RNA Export From Nucleus Metabolic Process Intestinal Epithelial Structure Maintenance	Retrograde Transport, Endosome To Golgi Synaptic Growth At Neuromuscular Junction Negative Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of Hydrolase Activity Endosomal Transport Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Translation Vesicle-mediated Transport Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Adrenergic Receptor Signaling Pathway Intracellular Transport Positive Regulation Of Catalytic Activity Axon Choice Point Recognition Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Neuron Remodeling Relaxation Of Vascular Smooth Muscle Retrograde Transport, Endosome To Plasma Membrane Relaxation Of Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Hydrolase Activity Positive Regulation Of Striated Muscle Contraction Negative Regulation Of Muscle Hypertrophy Transcytosis Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Microtubule Polymerization Relaxation Of Cardiac Muscle Establishment Of Localization In Cell Negative Regulation Of Smooth Muscle Contraction Cellular Copper Ion Homeostasis Positive Regulation Of Receptor Internalization Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Copper Ion Homeostasis Suckling Behavior Regulation Of Catalytic Activity Cellular Localization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cardiac Muscle Hypertrophy Regulation Of Receptor Internalization
Tagcloud ?			branched building cargo comprises coordinate dimer dysregulation endosomal endosome fam21 laboratories nexins operate recruits retromer rme snx1 sort sorting subcomplexes trimer tubulate tubulating tubulation tubules vital vps26 vps35 wash
Tagcloud (Difference) ?			branched building cargo comprises coordinate dimer dysregulation endosomal endosome fam21 laboratories nexins operate recruits retromer rme snx1 sort sorting subcomplexes trimer tubulate tubulating tubulation tubules vital vps26 vps35 wash
Tagcloud (Intersection) ?