FRA10AC1 and PRPF3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		FRA10AC1	PRPF3
Gene Name		fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	pre-mRNA processing factor 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process		Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ADPRHL2 C21orf33 C7orf25 CCDC155 CHERP CWC27 DGCR14 EEF1D GDPD2 GLRX3 HABP4 IK LPPR4 MAP3K12 MFAP1 NKAP PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830	24 interactors: BRCA1 CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GTPBP3 NHP2L1 NKAP PCBP1 PPIH PRPF31 PRPF4 RBM39 SART3 SNIP1 TRIM39 U2AF2 USP4 WBP4 ZCCHC10
Entrez ID		118924	9129
HPRD ID		12319	07389
Ensembl ID		ENSG00000148690	ENSG00000117360
Uniprot IDs		Q70Z53	E7EVD1 O43395
PDB IDs			1X4Q
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Chromosome Localization To Nuclear Envelope Involved In Synapsis Negative Regulation Of Isotype Switching To IgA Isotypes MRNA Export From Nucleus RNA Export From Nucleus Metabolic Process Intestinal Epithelial Structure Maintenance	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Metabolic Process Spliceosomal SnRNP Assembly Hematopoietic Stem Cell Proliferation Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Ribonucleoprotein Complex Biogenesis Metabolic Process Cochlea Morphogenesis Regulation Of Gene Expression Non-canonical Wnt Signaling Pathway Ribonucleoprotein Complex Assembly Regulation Of Protein Ubiquitination Cochlea Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone Deubiquitination Positive Regulation Of Histone H4-K16 Acetylation Outflow Tract Morphogenesis Positive Regulation Of Histone Modification Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of JUN Kinase Activity Cellular Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of JUN Kinase Activity Stem Cell Proliferation Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction In Response To DNA Damage RNA Biosynthetic Process Canonical Wnt Signaling Pathway Regulation Of Metabolic Process Inner Ear Morphogenesis Negative Regulation Of Protein Ubiquitination Non-canonical Wnt Signaling Pathway Via JNK Cascade
Tagcloud ?			accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Difference) ?			accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Intersection) ?