RHBDL2 and EFNB2

Number of citations of the paper that reports this interaction (PMID 15047175)
14

Data Source:
HPRD (in vitro)

		RHBDL2	EFNB2
Gene Name		rhomboid, veinlet-like 2 (Drosophila)	ephrin-B2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion
	Molecular Function	Serine-type Endopeptidase Activity	Protein Binding Ephrin Receptor Binding
	Biological Process	Proteolysis	Lymph Vessel Development Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Anatomical Structure Morphogenesis Organ Morphogenesis Negative Regulation Of Keratinocyte Proliferation Viral Process Ephrin Receptor Signaling Pathway Regulation Of Chemotaxis Positive Regulation Of Cardiac Muscle Cell Differentiation
Pathways			EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Menopause (age at onset) ( 22267201)
Protein-Protein Interactions		2 interactors: EFNB2 EFNB3	21 interactors: DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RGS3 RHBDL2 SDCBP SRC
Entrez ID		54933	1948
HPRD ID		07151	02754
Ensembl ID		ENSG00000158315	ENSG00000125266
Uniprot IDs		B3KUN4 B7Z1Y9 Q9NX52	P52799
PDB IDs			2HLE 2I85 2VSK 2VSM 2WO2 3GXU
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Axon Guidance Axonogenesis Axon Choice Point Recognition Viral Process Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Negative Regulation Of Keratinocyte Proliferation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Cell-cell Signaling Positive Regulation Of Cardiac Muscle Cell Differentiation Neuron Development Cell Migration Involved In Sprouting Angiogenesis Regulation Of Keratinocyte Proliferation Lymph Vessel Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Blood Vessel Endothelial Cell Migration Locomotion Neuron Recognition Movement Of Cell Or Subcellular Component Adult Walking Behavior Generation Of Neurons Sprouting Angiogenesis Neurogenesis Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Muscle Tissue Development Cell Development Response To External Stimulus Endothelial Cell Migration Positive Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Epithelial Cell Migration Epithelium Migration Nervous System Development Adult Locomotory Behavior Cell Recognition Anatomical Structure Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Regulation Of Striated Muscle Tissue Development	Ephrin Receptor Signaling Pathway Neuron Development Axon Guidance Neuron Differentiation Generation Of Neurons Neurogenesis Axonogenesis Cell Development Axon Development Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Projection Organization Neuron Projection Morphogenesis Regulation Of Signaling Locomotion Cell Morphogenesis Involved In Differentiation Nervous System Development Movement Of Cell Or Subcellular Component Cell Projection Morphogenesis Cell Part Morphogenesis Dendritic Spine Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Cell Differentiation Response To External Stimulus Cell Morphogenesis System Development Cell Migration Signal Transduction Synaptic Transmission Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Dendritic Spine Morphogenesis Cell Motility Regulation Of MAPK Cascade Multicellular Organismal Development Regulation Of Phosphorylation Signaling Cell Communication Anatomical Structure Development Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Component Organization Regulation Of Synaptic Transmission Dendritic Spine Development Regulation Of Synaptic Plasticity Developmental Process Behavior
Tagcloud ?			a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efna3 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53
Tagcloud (Difference) ?			a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efna3 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53
Tagcloud (Intersection) ?