EFNB2 and PDZRN3

Number of citations of the paper that reports this interaction (PMID 15458844)
39

Data Source:
HPRD (two hybrid)

		EFNB2	PDZRN3
Gene Name		ephrin-B2	PDZ domain containing ring finger 3
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion	Neuromuscular Junction
	Molecular Function	Protein Binding Ephrin Receptor Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Lymph Vessel Development Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Anatomical Structure Morphogenesis Organ Morphogenesis Negative Regulation Of Keratinocyte Proliferation Viral Process Ephrin Receptor Signaling Pathway Regulation Of Chemotaxis Positive Regulation Of Cardiac Muscle Cell Differentiation	Neuromuscular Junction Development Protein Ubiquitination
Pathways		EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS			Dialysis-related mortality ( 21546767)
Protein-Protein Interactions		21 interactors: DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RGS3 RHBDL2 SDCBP SRC	5 interactors: BMPR2 EFNB2 LNX1 LNX2 UBE2D2
Entrez ID		1948	23024
HPRD ID		02754	15115
Ensembl ID		ENSG00000125266	ENSG00000121440
Uniprot IDs		P52799	B7ZAG0 F5H8I9 Q9UPQ7
PDB IDs		2HLE 2I85 2VSK 2VSM 2WO2 3GXU	1UHP 1WH1
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Neuron Development Axon Guidance Neuron Differentiation Generation Of Neurons Neurogenesis Axonogenesis Cell Development Axon Development Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Projection Organization Neuron Projection Morphogenesis Regulation Of Signaling Locomotion Cell Morphogenesis Involved In Differentiation Nervous System Development Movement Of Cell Or Subcellular Component Cell Projection Morphogenesis Cell Part Morphogenesis Dendritic Spine Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Cell Differentiation Response To External Stimulus Cell Morphogenesis System Development Cell Migration Signal Transduction Synaptic Transmission Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Dendritic Spine Morphogenesis Cell Motility Regulation Of MAPK Cascade Multicellular Organismal Development Regulation Of Phosphorylation Signaling Cell Communication Anatomical Structure Development Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Component Organization Regulation Of Synaptic Transmission Dendritic Spine Development Regulation Of Synaptic Plasticity Developmental Process Behavior	Lymph Vessel Development Regulation Of Chemotaxis Regulation Of Lung Blood Pressure Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Vasoconstriction Regulation Of Behavior Protein Homooligomerization Regulation Of Epithelial Cell Proliferation Positive Regulation Of Axon Extension Involved In Axon Guidance Lymphatic Endothelial Cell Differentiation
Tagcloud ?		a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efna3 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53
Tagcloud (Difference) ?		a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efna3 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53
Tagcloud (Intersection) ?