RHBDL2 and EFNB3

Number of citations of the paper that reports this interaction (PMID 15047175)
14

Data Source:
HPRD (in vitro)

		RHBDL2	EFNB3
Gene Name		rhomboid, veinlet-like 2 (Drosophila)	ephrin-B3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Serine-type Endopeptidase Activity	Transmembrane-ephrin Receptor Activity Ephrin Receptor Binding
	Biological Process	Proteolysis	Cell-cell Signaling Nervous System Development Axon Guidance Adult Walking Behavior Viral Process Axon Choice Point Recognition Ephrin Receptor Signaling Pathway
Pathways			EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Menopause (age at onset) ( 22267201)
Protein-Protein Interactions		2 interactors: EFNB2 EFNB3	7 interactors: AATF EPHA4 EPHB3 P2RX7 RHBDL2 TCEB1 YWHAZ
Entrez ID		54933	1949
HPRD ID		07151	03804
Ensembl ID		ENSG00000158315	ENSG00000108947
Uniprot IDs		B3KUN4 B7Z1Y9 Q9NX52	Q15768
PDB IDs			4BKF
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Axon Guidance Axonogenesis Axon Choice Point Recognition Viral Process Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Negative Regulation Of Keratinocyte Proliferation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Cell-cell Signaling Positive Regulation Of Cardiac Muscle Cell Differentiation Neuron Development Cell Migration Involved In Sprouting Angiogenesis Regulation Of Keratinocyte Proliferation Lymph Vessel Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Blood Vessel Endothelial Cell Migration Locomotion Neuron Recognition Movement Of Cell Or Subcellular Component Adult Walking Behavior Generation Of Neurons Sprouting Angiogenesis Neurogenesis Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Muscle Tissue Development Cell Development Response To External Stimulus Endothelial Cell Migration Positive Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Epithelial Cell Migration Epithelium Migration Nervous System Development Adult Locomotory Behavior Cell Recognition Anatomical Structure Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Regulation Of Striated Muscle Tissue Development	Regulation Of Rac GTPase Activity Axonal Fasciculation Regulation Of Rac Protein Signal Transduction Neuron Recognition Central Nervous System Projection Neuron Axonogenesis Apoptotic Signaling Pathway Central Nervous System Neuron Axonogenesis Cell Adhesion Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity Ephrin Receptor Signaling Pathway Central Nervous System Neuron Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cell Recognition Positive Regulation Of Cell Death Phospholipid Transfer To Membrane NAD Transport Fasciculation Of Motor Neuron Axon Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Interleukin-1 Alpha Secretion Fasciculation Of Sensory Neuron Axon Regulation Of Axonogenesis Phosphorylation Positive Regulation Of Cytolysis Negative Regulation Of Axon Regeneration Golgi Reassembly Multicellular Organismal Protein Catabolic Process Regulation Of Cellular Component Organization Negative Regulation Of Superoxide Anion Generation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Glutamate Secretion Multicellular Organismal Protein Metabolic Process Positive Regulation Of MAP Kinase Activity Protein Autophosphorylation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Interleukin-1 Alpha Production Histamine Secretion By Mast Cell Central Nervous System Neuron Differentiation Establishment Of Golgi Localization Positive Regulation Of Gamma-aminobutyric Acid Secretion Positive Regulation Of Intracellular Transport Apoptotic Process Golgi Inheritance Programmed Cell Death Regulation Of Amyloid Precursor Protein Biosynthetic Process Cellular Response To Stimulus Cell Death Death Cell Morphogenesis Histamine Secretion
Tagcloud ?			131i anticancer b6 behind destabilization destabilizing egr1 eph epha2 ephb6 ephrin gadd45b lin metaiodobenzylguanidine metformin mibg miz mycn neuregulin nrg1 ntrk1 perp phenformin radiolabeled scintigraphic sel sel1l
Tagcloud (Difference) ?			131i anticancer b6 behind destabilization destabilizing egr1 eph epha2 ephb6 ephrin gadd45b lin metaiodobenzylguanidine metformin mibg miz mycn neuregulin nrg1 ntrk1 perp phenformin radiolabeled scintigraphic sel sel1l
Tagcloud (Intersection) ?