CD160 and TNFRSF14

Number of citations of the paper that reports this interaction (PMID 21982860)
4

Data Source:
BioGRID (pull down)

		CD160	TNFRSF14
Gene Name		CD160 molecule	tumor necrosis factor receptor superfamily, member 14
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Anchored Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Receptor Activity Receptor Binding MHC Class I Receptor Activity	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Cellular Defense Response Cell Surface Receptor Signaling Pathway Cell Proliferation Regulation Of Immune Response Defense Response To Gram-negative Bacterium	Positive Regulation Of Cytokine Secretion Involved In Immune Response Immune Response Cell Surface Receptor Signaling Pathway Response To Virus Viral Process T Cell Costimulation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of T Cell Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System	Costimulation by the CD28 family Adaptive Immune System
Drugs
Diseases
GWAS			Celiac disease ( 20190752) Rheumatoid arthritis ( 18794853 20453842) Ulcerative colitis ( 23128233 21297633)
Protein-Protein Interactions		3 interactors: AGTRAP MDM4 TNFRSF14	30 interactors: A2M APP BTLA CD160 CHD3 DGKD DRAP1 DYNLL1 ESR1 HDAC3 HDAC4 IMPA2 ITFG1 KIAA1377 LTA MBTPS1 NDUFS2 NRIP1 RAD21 SERPINA4 TNFSF13 TNFSF14 TRAF1 TRAF2 TRAF3 TRAF5 UBQLN4 VIM WDR73 ZBTB48
Entrez ID		11126	8764
HPRD ID		06833	04122
Ensembl ID		ENSG00000117281	ENSG00000157873
Uniprot IDs		B8PRF2 O95971 Q6FH89	Q92956
PDB IDs			1JMA 2AW2 4FHQ
Enriched GO Terms of Interacting Partners?		G0 To G1 Transition Response To Hypoxia Positive Regulation Of Cytokine Secretion Involved In Immune Response Negative Regulation Of Alpha-beta T Cell Proliferation Angiotensin-activated Signaling Pathway Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of T Cell Migration Negative Regulation Of Cell Cycle Arrest Negative Regulation Of Cell Proliferation Regulation Of T Cell Migration Negative Regulation Of Alpha-beta T Cell Activation Response To Stress Regulation Of Lymphocyte Migration Defense Response To Gram-negative Bacterium Tumor Necrosis Factor-mediated Signaling Pathway Viral Entry Into Host Cell Entry Into Host Cell Positive Regulation Of Cytokine Production Involved In Immune Response Response To Abiotic Stimulus	Signal Transduction Apoptotic Process Programmed Cell Death Signaling Cell Communication Cell Death Death Cellular Response To Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Process Response To Stimulus Regulation Of Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Proteolysis Regulation Of Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Immune Response Regulation Of Endopeptidase Activity Regulation Of Immune System Process Regulation Of Peptidase Activity Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Protein Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription Factor Import Into Nucleus Response To Stress Negative Regulation Of Endopeptidase Activity Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Peptidase Activity Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cell Activation Histone H4 Deacetylation Positive Regulation Of NF-kappaB Transcription Factor Activity Spindle Organization Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Immune System Process Immune System Process Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Protein Binding Negative Regulation Of Proteolysis Positive Regulation Of Adaptive Immune Response Positive Regulation Of Immunoglobulin Mediated Immune Response Histone H3 Deacetylation Negative Regulation Of Protein Processing Regulation Of Transcription From RNA Polymerase II Promoter Histone H3-K9 Modification Regulation Of Establishment Of Protein Localization
Tagcloud ?		activatory anchored antibodies antigenic bead capacities cd8 coexpression defines ex exhausted exhaustion functionality glycosylphosphatidylinositol gpi herpes hvem immunotherapeutic isoforms jurkat multimerization pbmcs reverses stimulatory synergistically tm triggering viremic warrant	aberrations additional advances approaches biological closely contribute crebbp ep300 epha7 expected ezh2 fl follicular genetic hallmark hand individuals lymphoma mef2b microenvironment mll2 pathogenesis recognized recurrent technology translocation understanding unique
Tagcloud (Difference) ?		activatory anchored antibodies antigenic bead capacities cd8 coexpression defines ex exhausted exhaustion functionality glycosylphosphatidylinositol gpi herpes hvem immunotherapeutic isoforms jurkat multimerization pbmcs reverses stimulatory synergistically tm triggering viremic warrant	aberrations additional advances approaches biological closely contribute crebbp ep300 epha7 expected ezh2 fl follicular genetic hallmark hand individuals lymphoma mef2b microenvironment mll2 pathogenesis recognized recurrent technology translocation understanding unique
Tagcloud (Intersection) ?