CD160 and CMTM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD160	CMTM6
Description		CD160 molecule	CKLF like MARVEL transmembrane domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Side Of Membrane	Endosome Plasma Membrane Membrane Early Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Recycling Endosome Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Signaling Receptor Binding Protein Binding Kinase Binding MHC Class I Protein Complex Binding MHC Class I Receptor Activity MHC Class Ib Receptor Activity Activating MHC Class I Receptor Activity	Protein Binding
	Biological Process	Angiogenesis Positive Regulation Of Cytokine Production Adaptive Immune Response Immune System Process Mucosal Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Natural Killer Cell Cytokine Production Regulation Of Adaptive Immune Response Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Negative Regulation Of Angiogenesis T Cell Costimulation Positive Regulation Of Type II Interferon Production Positive Regulation Of Natural Killer Cell Degranulation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Gram-negative Bacterium Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Negative Regulation Of Adaptive Immune Memory Response Positive Regulation Of Endothelial Cell Apoptotic Process	Protein Transport Regulation Of Protein Stability Endocytic Recycling
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Neutrophil degranulation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653)	Apolipoprotein B levels ( 32203549) Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Cholesterol, total ( 24097068) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 28334899 32203549) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 28334899 30275531)
Interacting Genes		8 interacting genes: AGTRAP CMTM5 CMTM6 MAL2 MDM4 SYP THRA TNFRSF14	23 interacting genes: APOA5 ATP13A2 BPIFA2 CD160 CD40 CIAO2A COQ8A DNMT3B DUSP10 ECPAS EHHADH FAM9B MIEF1 PPBP RBFA RBMX RUSC1 SNRPB2 SPG21 SUMO2 TCEA2 TMED8 XRCC6
Entrez ID		11126	54918
HPRD ID		06833	06987
Ensembl ID		ENSG00000117281	ENSG00000091317
Uniprot IDs		O95971 Q6FH89	Q9NX76
PDB IDs		6NG3 6NG9 6NGG 7MSG
Enriched GO Terms of Interacting Partners?
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