TTC19 and UPF3B

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TTC19	UPF3B
Gene Name		tetratricopeptide repeat domain 19	UPF3 regulator of nonsense transcripts homolog B (yeast)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody	Nucleus Nucleoplasm Cytoplasm Cytosol Exon-exon Junction Complex
	Molecular Function	Protein Binding	Nucleotide Binding MRNA Binding Nucleocytoplasmic Transporter Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of Translation
Pathways			Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ATXN1 CCDC33 CCDC36 CHMP4A EIF4ENIF1 HPS6 L3MBTL3 NAB2 REL SPRED1 UBA1 UPF3B	10 interactors: EIF6 EXOSC4 HBB MCRS1 RBBP6 RBM8A TTC19 UPF1 UPF2 XRN1
Entrez ID		54902	65109
HPRD ID		07899	02247
Ensembl ID		ENSG00000011295	ENSG00000125351
Uniprot IDs		Q6DKK2	Q9BZI7
PDB IDs			1UW4 2XB2
Enriched GO Terms of Interacting Partners?			Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Histone MRNA Catabolic Process RNA Catabolic Process Histone MRNA Metabolic Process Nuclear Export Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Catabolic Process MRNA Export From Nucleus Nuclear MRNA Surveillance Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus RNA Surveillance Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Transport RNA Transport RNA Localization Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Gene Expression Cytoplasmic Transport Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Nitric Oxide Transport RRNA Metabolic Process Mature Ribosome Assembly Intracellular Transport Ribosome Biogenesis Cellular Metabolic Process DNA Deamination Ribosomal Subunit Export From Nucleus Mitochondrial Respiratory Chain Complex III Assembly Dosage Compensation By Inactivation Of X Chromosome Regulation Of Translational Termination RRNA Catabolic Process Nucleobase-containing Compound Metabolic Process Dosage Compensation Renal Absorption Regulation Of Translation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Heterocycle Metabolic Process Histone H4-K16 Acetylation Cellular Aromatic Compound Metabolic Process Establishment Of Localization In Cell Nucleic Acid Phosphodiester Bond Hydrolysis Maturation Of 5.8S RRNA
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