BEST2 and MALL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BEST2	MALL
Description		bestrophin 2	mal, T cell differentiation protein like
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Basolateral Plasma Membrane Chloride Channel Complex	Golgi Membrane Plasma Membrane Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft
	Molecular Function	Intracellularly Ligand-gated Monoatomic Ion Channel Activity Chloride Channel Activity Protein Binding Channel Activity Metal Ion Binding Ligand-gated Monoatomic Cation Channel Activity Ligand-gated Monoatomic Anion Channel Activity Bicarbonate Channel Activity	Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Monoatomic Ion Transport Chloride Transport Sensory Perception Of Smell Bicarbonate Transport Monoatomic Ion Transmembrane Transport Membrane Depolarization Monoatomic Cation Transmembrane Transport Chloride Transmembrane Transport	Myelination Cholesterol Homeostasis
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: CLDN10 COMT CYB561 DNAJC30 EFNA5 FXYD3 GPR25 MALL PNLIPRP1 RFT1 SLC61A1 SLC66A2 TMEM128 TMEM60 UNC93B1 UPK1B	69 interacting genes: AMIGO1 AQP6 ARL13B ATP5PF BEST2 BNIP3 BNIP3L BRI3 BSCL2 CAV1 CAV2 CD79A CLDN7 CLDN9 CLEC10A CLEC12B CLEC14A CPLX4 CREB3 CREB3L1 CRHR2 CTLA4 DAGLA DCBLD2 ELOVL2 ELOVL4 EMP1 ERGIC3 EVI2A FCGR1A FFAR2 FNDC9 GGT7 GJA8 GPA33 IL7R KASH5 KLRC1 LDLRAD1 LEPROTL1 LMNA MANBAL MCEMP1 MS4A12 MSR1 MUC1 OPRM1 PGRMC2 PLA2G2E RETREG3 RNF185 SIGLEC6 SIT1 SLC10A1 SLC10A6 SLC18A1 SLC35H1 STMN4 STX1A SYNE4 SYT2 TMEM139 TMEM182 TMEM248 TMEM31 TMEM80 TMX2 UBE2I ZP3
Entrez ID		54831	7851
HPRD ID		09548	15997
Ensembl ID		ENSG00000039987	ENSG00000144063
Uniprot IDs		Q8NFU1	Q13021
PDB IDs		8D1E 8D1F 8D1G 8D1H 9DYH 9DYI 9DYJ 9DYK 9DYN 9DYO
Enriched GO Terms of Interacting Partners?		Membrane Norepinephrine Secretion Catechol O-methyltransferase Activity Response To Food Neurotrophin TRKC Receptor Binding Neurotrophin TRKB Receptor Binding Lipid Translocation Regulation Of Membrane Lipid Distribution Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Glycolipid Translocation Glycolipid Floppase Activity	Membrane Protein Binding Plasma Membrane Caveolar Macromolecular Signaling Complex Nuclear Envelope Adaptive Immune Response Natural Killer Cell Inhibitory Signaling Pathway Endoplasmic Reticulum-autophagosome Adaptor Activity Carbohydrate Binding External Side Of Plasma Membrane Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Acute Inflammatory Response Bile Acid:sodium Symporter Activity Membrane Organization Immune Response-regulating Signaling Pathway Lipid Storage Positive Regulation Of Hypersensitivity Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Substrate Localization To Autophagosome Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Fatty Acid Elongation, Saturated Fatty Acid Mitochondrial Outer Membrane Permeabilization Caveola Assembly Organic Hydroxy Compound Transport Regulation Of Response To Endoplasmic Reticulum Stress Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Regulation Of Calcium Ion-dependent Exocytosis Mitochondrial Protein Catabolic Process Plasma Membrane Raft Assembly Negative Regulation Of T Cell Mediated Cytotoxicity Meiotic Nuclear Membrane Microtubule Tethering Complex Regulation Of Acute Inflammatory Response Immune Response-inhibiting Signal Transduction
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