MALL and BRI3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MALL	BRI3
Description		mal, T cell differentiation protein like	brain protein I3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft	Nucleus Cytoplasm Lysosome Lysosomal Membrane Plasma Membrane Membrane Azurophil Granule Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding Identical Protein Binding
	Biological Process	Myelination Cholesterol Homeostasis
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		69 interacting genes: AMIGO1 AQP6 ARL13B ATP5PF BEST2 BNIP3 BNIP3L BRI3 BSCL2 CAV1 CAV2 CD79A CLDN7 CLDN9 CLEC10A CLEC12B CLEC14A CPLX4 CREB3 CREB3L1 CRHR2 CTLA4 DAGLA DCBLD2 ELOVL2 ELOVL4 EMP1 ERGIC3 EVI2A FCGR1A FFAR2 FNDC9 GGT7 GJA8 GPA33 IL7R KASH5 KLRC1 LDLRAD1 LEPROTL1 LMNA MANBAL MCEMP1 MS4A12 MSR1 MUC1 OPRM1 PGRMC2 PLA2G2E RETREG3 RNF185 SIGLEC6 SIT1 SLC10A1 SLC10A6 SLC18A1 SLC35H1 STMN4 STX1A SYNE4 SYT2 TMEM139 TMEM182 TMEM248 TMEM31 TMEM80 TMX2 UBE2I ZP3	3 interacting genes: ABHD16A BACE1 MALL
Entrez ID		7851	25798
HPRD ID		15997	16562
Ensembl ID		ENSG00000144063	ENSG00000164713
Uniprot IDs		Q13021	O95415
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Caveolar Macromolecular Signaling Complex Nuclear Envelope Adaptive Immune Response Natural Killer Cell Inhibitory Signaling Pathway Endoplasmic Reticulum-autophagosome Adaptor Activity Carbohydrate Binding External Side Of Plasma Membrane Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Acute Inflammatory Response Bile Acid:sodium Symporter Activity Membrane Organization Immune Response-regulating Signaling Pathway Lipid Storage Positive Regulation Of Hypersensitivity Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Substrate Localization To Autophagosome Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Fatty Acid Elongation, Saturated Fatty Acid Mitochondrial Outer Membrane Permeabilization Caveola Assembly Organic Hydroxy Compound Transport Regulation Of Response To Endoplasmic Reticulum Stress Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Regulation Of Calcium Ion-dependent Exocytosis Mitochondrial Protein Catabolic Process Plasma Membrane Raft Assembly Negative Regulation Of T Cell Mediated Cytotoxicity Meiotic Nuclear Membrane Microtubule Tethering Complex Regulation Of Acute Inflammatory Response Immune Response-inhibiting Signal Transduction	Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Golgi-associated Vesicle Lumen Beta-aspartyl-peptidase Activity Membrane Raft Monoacylglycerol Catabolic Process Structural Constituent Of Myelin Sheath Monoacylglycerol Lipase Activity Phospholipase Activity Phosphatidylserine Metabolic Process Acylglycerol Catabolic Process Glycerophospholipid Catabolic Process Phosphatidylcholine Lysophospholipase Activity Prepulse Inhibition Membrane Protein Ectodomain Proteolysis Amyloid-beta Formation Aspartic-type Endopeptidase Activity Response To Manganese Ion Amyloid Precursor Protein Metabolic Process Amyloid Precursor Protein Catabolic Process Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Cellular Response To Copper Ion Amyloid-beta Metabolic Process Response To Lead Ion Cellular Response To Manganese Ion Protein Serine/threonine Kinase Binding Detection Of Mechanical Stimulus Involved In Sensory Perception Amyloid Fibril Formation Modified Amino Acid Catabolic Process Response To Copper Ion Membrane Protein Proteolysis Cytoplasmic Vesicle Phospholipid Catabolic Process Presynaptic Modulation Of Chemical Synaptic Transmission Detection Of Mechanical Stimulus Hippocampal Mossy Fiber To CA3 Synapse Multivesicular Body Signaling Receptor Ligand Precursor Processing Cellular Response To Amyloid-beta Response To Amyloid-beta Positive Regulation Of Neuron Apoptotic Process Clathrin-coated Vesicle Fatty Acid Derivative Metabolic Process Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Endopeptidase Activity Amyloid-beta Binding Sterol Homeostasis Cholesterol Homeostasis Myelination
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