BEST2 and TMEM128

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BEST2	TMEM128
Description		bestrophin 2	transmembrane protein 128
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Basolateral Plasma Membrane Chloride Channel Complex	Membrane
	Molecular Function	Intracellularly Ligand-gated Monoatomic Ion Channel Activity Chloride Channel Activity Protein Binding Channel Activity Metal Ion Binding Ligand-gated Monoatomic Cation Channel Activity Ligand-gated Monoatomic Anion Channel Activity Bicarbonate Channel Activity	Protein Binding
	Biological Process	Monoatomic Ion Transport Chloride Transport Sensory Perception Of Smell Bicarbonate Transport Monoatomic Ion Transmembrane Transport Membrane Depolarization Monoatomic Cation Transmembrane Transport Chloride Transmembrane Transport
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS			Glomerular filtration rate ( 24351856)
Interacting Genes		16 interacting genes: CLDN10 COMT CYB561 DNAJC30 EFNA5 FXYD3 GPR25 MALL PNLIPRP1 RFT1 SLC61A1 SLC66A2 TMEM128 TMEM60 UNC93B1 UPK1B	66 interacting genes: AQP6 ARL13B BCL2L13 BEST2 CD40 CD53 CD79A CLDN5 CLDN7 CLN8 CPLX4 CREB3L1 CYB561 CYBC1 ELOVL4 ERGIC3 FAM209A FFAR2 GAD2 GJA1 GJA8 GJB5 GORAB GPR152 GPR42 GPX8 HSD17B11 HSD17B13 IER3IP1 IL3RA JAGN1 KCNK5 LEUTX LHFPL2 LHFPL5 LMNA MAPK8IP2 MFF MRPS18B MTERF1 MTIF3 MUC1 REEP4 RETREG3 SCN3B SEC11C SHISAL1 SLC10A6 SLC18A1 SLC1A3 SLC26A6 SLC34A2 SLC35H1 SLC61A1 SLC7A14 SSMEM1 STX1A TMEM106A TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 TMX2 ZDHHC15 ZFYVE27
Entrez ID		54831	85013
HPRD ID		09548	17483
Ensembl ID		ENSG00000039987	ENSG00000132406
Uniprot IDs		Q8NFU1	B7Z3K1 Q5BJH2
PDB IDs		8D1E 8D1F 8D1G 8D1H 9DYH 9DYI 9DYJ 9DYK 9DYN 9DYO
Enriched GO Terms of Interacting Partners?		Membrane Norepinephrine Secretion Catechol O-methyltransferase Activity Response To Food Neurotrophin TRKC Receptor Binding Neurotrophin TRKB Receptor Binding Lipid Translocation Regulation Of Membrane Lipid Distribution Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Glycolipid Translocation Glycolipid Floppase Activity	Membrane Protein Binding Endoplasmic Reticulum Organization Endoplasmic Reticulum Transmembrane Transport Inorganic Anion Transport Acidic Amino Acid Transport Neurotransmitter Transport Endoplasmic Reticulum Membrane Connexin Complex Steroid Dehydrogenase Activity Organic Anion Transport Gap Junction Channel Activity Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Plasma Membrane Gap Junction Monoatomic Ion Transport Dicarboxylic Acid Transport Neurotransmitter Uptake Gamma-aminobutyric Acid Biosynthetic Process Gamma-aminobutyric Acid Metabolic Process Carboxylic Acid Transport Organic Acid Transport Atrial Cardiac Muscle Cell Action Potential Chloride Transmembrane Transport Chloride Transport L-glutamate Import Across Plasma Membrane Efflux Transmembrane Transporter Activity
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