MALL and CLEC12B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MALL	CLEC12B
Description		mal, T cell differentiation protein like	C-type lectin domain family 12 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft	Plasma Membrane External Side Of Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding Protein Phosphatase Binding Carbohydrate Binding Signaling Receptor Regulator Activity Signaling Receptor Inhibitor Activity
	Biological Process	Myelination Cholesterol Homeostasis	Natural Killer Cell Inhibitory Signaling Pathway Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Melanocyte Proliferation Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Signaling Receptor Activity
Pathways
Drugs
Diseases
GWAS			Malaria ( 31844061) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes		69 interacting genes: AMIGO1 AQP6 ARL13B ATP5PF BEST2 BNIP3 BNIP3L BRI3 BSCL2 CAV1 CAV2 CD79A CLDN7 CLDN9 CLEC10A CLEC12B CLEC14A CPLX4 CREB3 CREB3L1 CRHR2 CTLA4 DAGLA DCBLD2 ELOVL2 ELOVL4 EMP1 ERGIC3 EVI2A FCGR1A FFAR2 FNDC9 GGT7 GJA8 GPA33 IL7R KASH5 KLRC1 LDLRAD1 LEPROTL1 LMNA MANBAL MCEMP1 MS4A12 MSR1 MUC1 OPRM1 PGRMC2 PLA2G2E RETREG3 RNF185 SIGLEC6 SIT1 SLC10A1 SLC10A6 SLC18A1 SLC35H1 STMN4 STX1A SYNE4 SYT2 TMEM139 TMEM182 TMEM248 TMEM31 TMEM80 TMX2 UBE2I ZP3	11 interacting genes: IL1RL1 JAGN1 LPAR3 LSMEM2 MALL OPRM1 PLLP PMP22 SCD SEC22A VMA21
Entrez ID		7851	387837
HPRD ID		15997	18266
Ensembl ID		ENSG00000144063	ENSG00000256660
Uniprot IDs		Q13021	A0A140VK10 Q2HXU8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Caveolar Macromolecular Signaling Complex Nuclear Envelope Adaptive Immune Response Natural Killer Cell Inhibitory Signaling Pathway Endoplasmic Reticulum-autophagosome Adaptor Activity Carbohydrate Binding External Side Of Plasma Membrane Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Acute Inflammatory Response Bile Acid:sodium Symporter Activity Membrane Organization Immune Response-regulating Signaling Pathway Lipid Storage Positive Regulation Of Hypersensitivity Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Substrate Localization To Autophagosome Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Fatty Acid Elongation, Saturated Fatty Acid Mitochondrial Outer Membrane Permeabilization Caveola Assembly Organic Hydroxy Compound Transport Regulation Of Response To Endoplasmic Reticulum Stress Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Regulation Of Calcium Ion-dependent Exocytosis Mitochondrial Protein Catabolic Process Plasma Membrane Raft Assembly Negative Regulation Of T Cell Mediated Cytotoxicity Meiotic Nuclear Membrane Microtubule Tethering Complex Regulation Of Acute Inflammatory Response Immune Response-inhibiting Signal Transduction	Compact Myelin Myelination Axon Ensheathment Bleb Assembly Structural Constituent Of Myelin Sheath Membrane Myelin Assembly G-protein Alpha-subunit Binding G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Monounsaturated Fatty Acid Biosynthetic Process Interleukin-33 Binding Negative Regulation Of Protein Secretion Palmitoyl-CoA 9-desaturase Activity Interleukin-33 Receptor Activity Regulation Of Transcytosis Endoplasmic Reticulum Cellular Response To Morphine Stearoyl-CoA 9-desaturase Activity Regulation Of NMDA Receptor Activity Lysophosphatidic Acid Receptor Activity Negative Regulation Of Protein Transport Endoplasmic Reticulum Membrane Granulocyte Colony-stimulating Factor Signaling Pathway Vacuolar Proton-transporting V-type ATPase Complex Assembly Negative Regulation Of Establishment Of Protein Localization Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water Interleukin-1 Receptor Activity Myeloid Leukocyte Differentiation Negative Regulation Of Secretion By Cell
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