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ZBTB14 and POLR2L
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
ZBTB14
POLR2L
Gene Name
zinc finger and BTB domain containing 14
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nucleus
Nucleoplasm
DNA-directed RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase III Complex
DNA-directed RNA Polymerase I Complex
Cytosol
Molecular Function
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Metal Ion Binding
RNA Polymerase I Activity
RNA Polymerase II Activity
RNA Polymerase III Activity
DNA Binding
DNA-directed RNA Polymerase Activity
Zinc Ion Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Negative Regulation Of Transcription, DNA-templated
MRNA Splicing, Via Spliceosome
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Regulation Of Transcription From RNA Polymerase I Promoter
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Transcription From RNA Polymerase III Promoter
Transcription Elongation From RNA Polymerase III Promoter
Termination Of RNA Polymerase III Transcription
RNA Splicing
Gene Expression
Viral Process
Positive Regulation Of Type I Interferon Production
PiRNA Metabolic Process
Somatic Stem Cell Maintenance
Regulation Of Gene Expression, Epigenetic
Innate Immune Response
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Regulatory RNA pathways
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
Formation of transcription-coupled NER (TC-NER) repair complex
Dual incision reaction in TC-NER
Influenza Life Cycle
RNA Polymerase III Transcription Termination
HIV elongation arrest and recovery
NoRC negatively regulates rRNA expression
Influenza Viral RNA Transcription and Replication
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation From Type 1 Promoter
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
MicroRNA (miRNA) biogenesis
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
RNA Polymerase III Transcription Initiation From Type 2 Promoter
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Abortive And Retractive Initiation
Transcription of the HIV genome
Nucleotide Excision Repair
PIWI-interacting RNA (piRNA) biogenesis
mRNA Splicing
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase II Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
HIV Infection
Formation of the Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Transcriptional regulation of pluripotent stem cells
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Innate Immune System
RNA Polymerase III Transcription Initiation
Transcriptional regulation by small RNAs
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Cytosolic sensors of pathogen-associated DNA
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Pausing and recovery of HIV elongation
Formation of the HIV-1 Early Elongation Complex
Viral Messenger RNA Synthesis
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
AP1M1
ATP5O
BAZ2B
BYSL
CBX8
CDK16
CDKL3
CEP19
EAF1
EIF1AD
ENKD1
EPM2AIP1
FAM161A
FAM90A1
GORASP2
INTS3
KAT5
MAD2L1BP
MFAP1
MORF4L2
NAA10
PIN1
PNKP
POLR2L
PRMT1
RNPS1
RPL9
RPS7
SCNM1
SDCBP
SNRPB2
SYT16
TCEANC
TXN2
ZBTB21
ZCCHC10
ZMAT2
23 interactors:
BANP
CCDC85B
CHEK2
COIL
EXOSC5
L3MBTL3
NFKBIB
NOV
PHC2
POLR2A
POLR2B
POLR2C
POLR2D
POLR2E
POLR2G
POLR2H
REL
RPAP1
SNX7
SPAG5
THAP1
TP53BP2
ZBTB14
Entrez ID
7541
5441
HPRD ID
03674
01155
Ensembl ID
ENSG00000198081
ENSG00000177700
Uniprot IDs
B2R850
O43829
P62875
PDB IDs
Enriched GO Terms of Interacting Partners
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RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
MRNA Metabolic Process
RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Cellular Metabolic Process
Viral Process
Cellular Process
Nuclear-transcribed MRNA Catabolic Process
DNA Repair
RNA Splicing
MRNA Catabolic Process
Protein Targeting To Membrane
Ribosomal Small Subunit Biogenesis
RNA Catabolic Process
Biosynthetic Process
Transcription, DNA-templated
MRNA Processing
Aromatic Compound Catabolic Process
N-terminal Peptidyl-glutamic Acid Acetylation
Polynucleotide 3' Dephosphorylation
N-terminal Peptidyl-serine Acetylation
NcRNA Metabolic Process
Translational Initiation
MRNA Splicing, Via Spliceosome
Establishment Of Protein Localization To Membrane
Establishment Of Localization In Cell
RNA Splicing, Via Transesterification Reactions
Dendrite Extension
DNA-templated Transcription, Termination
Cellular Response To DNA Damage Stimulus
Cellular Macromolecule Catabolic Process
Positive Regulation Of Extracellular Vesicular Exosome Assembly
7-methylguanosine MRNA Capping
PiRNA Metabolic Process
7-methylguanosine RNA Capping
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
Transcription Elongation From RNA Polymerase II Promoter
Somatic Stem Cell Maintenance
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
DNA-templated Transcription, Elongation
Nucleotide-excision Repair
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Stem Cell Maintenance
Regulation Of Viral Process
Gene Expression
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Stem Cell Development
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
NcRNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Stem Cell Differentiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
MRNA Metabolic Process
RNA Splicing
Cellular Nitrogen Compound Metabolic Process
DNA Repair
Transcription From RNA Polymerase II Promoter
MRNA Processing
Nitrogen Compound Metabolic Process
Biosynthetic Process
Negative Regulation Of Cell Differentiation
DNA Metabolic Process
Regulation Of Gene Expression
Regulation Of RNA Biosynthetic Process
Viral Process
Cellular Response To DNA Damage Stimulus
Regulation Of RNA Metabolic Process
RNA Processing
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Cell Development
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Tagcloud (Intersection)
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