ZBTB14 and B4GALT6

		ZBTB14	B4GALT6
Description		zinc finger and BTB domain containing 14	beta-1,4-galactosyltransferase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Galactosyltransferase Activity UDP-galactose:glucosylceramide Beta-1,4-galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Kidney Development Regulation Of Immune System Process Heart Valve Development Cardiac Septum Development Negative Regulation Of DNA-templated Transcription Coronary Vasculature Development	Lactosylceramide Biosynthetic Process Carbohydrate Metabolic Process Protein Glycosylation Lipid Metabolic Process Sphingolipid Metabolic Process Glycosphingolipid Biosynthetic Process Ganglioside Biosynthetic Process Via Lactosylceramide Central Nervous System Neuron Axonogenesis Central Nervous System Myelination Neuron Maturation Glycosylation Carbohydrate Derivative Biosynthetic Process
Pathways			Keratan sulfate biosynthesis O-linked glycosylation of mucins N-Glycan antennae elongation Glycosphingolipid biosynthesis
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Lacunar stroke ( 33773637)	Amyotrophic lateral sclerosis ( 19451621) Blood protein levels ( 30072576) Free thyroxine concentration ( 25743335) Nicotine dependence symptom count ( 25555482) Problematic alcohol use in trauma-exposed individuals ( 29082582)
Interacting Genes		51 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 OGT PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2
Entrez ID		7541	9331
HPRD ID		03674	06808
Ensembl ID		ENSG00000198081	ENSG00000118276
Uniprot IDs		B2R850 O43829	G3XA83 Q59GB5 Q8WZ95 Q9UBX8
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Macromolecule Metabolic Process Nucleic Acid Metabolic Process Regulation Of Double-strand Break Repair Regulation Of DNA Repair Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Site Of Double-strand Break Protein N-terminal-serine Acetyltransferase Activity Nucleotide-excision Repair Protein Binding DNA Repair Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Recombinational Repair Positive Regulation Of DNA Repair Double-strand Break Repair Double-strand Break Repair Via Homologous Recombination Mismatch Repair NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Acetylation Positive Regulation Of Double-strand Break Repair Positive Regulation Of Mitotic Sister Chromatid Segregation Positive Regulation Of Double-strand Break Repair Via Homologous Recombination G-rich Strand Telomeric DNA Binding RNA Processing MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome N-terminal Protein Amino Acid Acetylation Clathrin Adaptor Complex Organelle Assembly RNA Splicing, Via Transesterification Reactions DNA Replication Factor A Complex Cytoplasmic Translation RNA Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Process	Aggresome Heart Valve Development Coronary Vasculature Development Cardiac Septum Development
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