ZBTB14 and RNASEH2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB14	RNASEH2B
Description		zinc finger and BTB domain containing 14	ribonuclease H2 subunit B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome	Nucleus Nucleoplasm Ribonuclease H2 Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Kidney Development Regulation Of Immune System Process Heart Valve Development Cardiac Septum Development Negative Regulation Of DNA-templated Transcription Coronary Vasculature Development	In Utero Embryonic Development Nucleobase-containing Compound Metabolic Process Mismatch Repair RNA Catabolic Process Ribonucleotide Metabolic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Gene Expression Negative Regulation Of Gene Expression Fibroblast Proliferation Positive Regulation Of Fibroblast Proliferation Regulation Of DNA Damage Checkpoint
Pathways
Drugs
Diseases			Aicardi-Goutieres Syndrome (AGS)
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Lacunar stroke ( 33773637)	Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Metabolite levels ( 23823483) Rheumatoid arthritis (ACPA-negative) ( 24532677) Systolic blood pressure ( 30224653)
Interacting Genes		51 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 OGT PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2	2 interacting genes: WT1 ZBTB14
Entrez ID		7541	79621
HPRD ID		03674	07757
Ensembl ID		ENSG00000198081	ENSG00000136104
Uniprot IDs		B2R850 O43829	A0A087WXR7 A0A2R8Y883 Q5TBB1 Q8N451
PDB IDs			3P56 3P87 3PUF 8YJZ
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Macromolecule Metabolic Process Nucleic Acid Metabolic Process Regulation Of Double-strand Break Repair Regulation Of DNA Repair Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Site Of Double-strand Break Protein N-terminal-serine Acetyltransferase Activity Nucleotide-excision Repair Protein Binding DNA Repair Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Recombinational Repair Positive Regulation Of DNA Repair Double-strand Break Repair Double-strand Break Repair Via Homologous Recombination Mismatch Repair NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Acetylation Positive Regulation Of Double-strand Break Repair Positive Regulation Of Mitotic Sister Chromatid Segregation Positive Regulation Of Double-strand Break Repair Via Homologous Recombination G-rich Strand Telomeric DNA Binding RNA Processing MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome N-terminal Protein Amino Acid Acetylation Clathrin Adaptor Complex Organelle Assembly RNA Splicing, Via Transesterification Reactions DNA Replication Factor A Complex Cytoplasmic Translation RNA Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Process	Kidney Development Transcription Cis-regulatory Region Binding Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Hemi-methylated DNA-binding Metanephric S-shaped Body Morphogenesis Negative Regulation Of Cell Proliferation Involved In Kidney Development Thorax And Anterior Abdomen Determination Double-stranded Methylated DNA Binding Diaphragm Development Regulation Of Female Gonad Development Sequence-specific DNA Binding Positive Regulation Of Male Gonad Development S-shaped Body Morphogenesis Cardiac Muscle Cell Fate Commitment Metanephric Mesenchyme Development Sequence-specific Double-stranded DNA Binding Metanephric Epithelium Development Muscle Cell Fate Commitment Nephron Tubule Morphogenesis Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Glomerulus Development Podocyte Differentiation C2H2 Zinc Finger Domain Binding Glomerular Basement Membrane Development Regulation Of Glomerular Mesangial Cell Proliferation DNA-binding Transcription Factor Activity Male Genitalia Development Mesenchymal To Epithelial Transition Renal Tubule Morphogenesis Skeletal Muscle Organ Development Cellular Response To Gonadotropin Stimulus Circulatory System Development Sex Determination Reproductive System Development Adrenal Gland Development Heart Valve Development Nucleolus Coronary Vasculature Development Response To Gonadotropin Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Animal Organ Formation Cell Differentiation Involved In Kidney Development Aggresome
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?