ZBTB14 and MAD2L1BP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB14	MAD2L1BP
Description		zinc finger and BTB domain containing 14	MAD2L1 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome	Nucleus Nucleoplasm Nucleolus Cytoplasm Spindle Cytoskeleton Nuclear Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Kidney Development Regulation Of Immune System Process Heart Valve Development Cardiac Septum Development Negative Regulation Of DNA-templated Transcription Coronary Vasculature Development	Regulation Of Exit From Mitosis Deactivation Of Mitotic Spindle Assembly Checkpoint
Pathways
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Lacunar stroke ( 33773637)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		51 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 OGT PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2	18 interacting genes: ANAPC4 CEP126 EEF1A1 HOMEZ IGSF21 KAT5 KRT15 LRIF1 MAD2L1 MAD2L2 NMI PLK1 PTN SETDB1 TP53 TRIP13 ZBTB14 ZNF202
Entrez ID		7541	9587
HPRD ID		03674	10065
Ensembl ID		ENSG00000198081	ENSG00000124688
Uniprot IDs		B2R850 O43829	Q15013
PDB IDs			2QYF 6F0X
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Macromolecule Metabolic Process Nucleic Acid Metabolic Process Regulation Of Double-strand Break Repair Regulation Of DNA Repair Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Site Of Double-strand Break Protein N-terminal-serine Acetyltransferase Activity Nucleotide-excision Repair Protein Binding DNA Repair Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Recombinational Repair Positive Regulation Of DNA Repair Double-strand Break Repair Double-strand Break Repair Via Homologous Recombination Mismatch Repair NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Acetylation Positive Regulation Of Double-strand Break Repair Positive Regulation Of Mitotic Sister Chromatid Segregation Positive Regulation Of Double-strand Break Repair Via Homologous Recombination G-rich Strand Telomeric DNA Binding RNA Processing MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome N-terminal Protein Amino Acid Acetylation Clathrin Adaptor Complex Organelle Assembly RNA Splicing, Via Transesterification Reactions DNA Replication Factor A Complex Cytoplasmic Translation RNA Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Process	Regulation Of Sister Chromatid Segregation Regulation Of Chromosome Segregation Regulation Of Chromosome Organization Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Chromosome Organization Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Mitotic Nuclear Division Chromosome Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Chromosome Separation Negative Regulation Of Mitotic Cell Cycle Regulation Of Ubiquitin-protein Transferase Activity Double-strand Break Repair Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Mitotic Nuclear Division Establishment Of Mitotic Spindle Orientation Negative Regulation Of Cell Cycle Process Microtubule Cytoskeleton Organization Involved In Mitosis Establishment Of Mitotic Spindle Localization Negative Regulation Of Double-strand Break Repair Regulation Of Mitotic Cell Cycle Negative Regulation Of DNA Metabolic Process Negative Regulation Of DNA Repair Establishment Of Spindle Orientation Regulation Of Nuclear Division Negative Regulation Of Macromolecule Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of DNA Recombination Chromosome Organization Establishment Of Spindle Localization Negative Regulation Of Cell Cycle Nucleus Negative Regulation Of Macromolecule Biosynthetic Process Nucleolus Negative Regulation Of Metabolic Process Negative Regulation Of Ubiquitin Protein Ligase Activity Spindle Localization Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Germ Cell Development Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Transferase Activity Promoter-specific Chromatin Binding Regulation Of Cell Cycle
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