ZNF562 and FBXL12

		ZNF562	FBXL12
Description		zinc finger protein 562	F-box and leucine rich repeat protein 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Ubiquitin Ligase Complex Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways		Generic Transcription Pathway	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Pursuit maintenance gain ( 29064472)
Interacting Genes			19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3
Entrez ID		54811	54850
HPRD ID		15844	12363
Ensembl ID		ENSG00000171466	ENSG00000127452
Uniprot IDs		B4DMG0 B4E2P7 K7EIE6 Q6V9R5	Q9NXK8
PDB IDs
Enriched GO Terms of Interacting Partners?			Amyloid Precursor Protein Metabolic Process Positive Regulation Of Amyloid Fibril Formation Aspartic Endopeptidase Activity, Intramembrane Cleaving Gamma-secretase Complex Notch Receptor Processing Amyloid-beta Formation Regulation Of Amyloid Fibril Formation I-SMAD Binding Amyloid Precursor Protein Catabolic Process
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