KLHDC4 and CEP76

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KLHDC4	CEP76
Gene Name		kelch domain containing 4	centrosomal protein 76kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Centrosome Centriole Cytosol Protein Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Regulation Of Centriole Replication
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CEP76 KDM1A SUV39H1 SUV39H2 TERF1	48 interactors: AKAP7 BANP BZRAP1 C22orf39 CABP5 CCDC92 CCNK CIR1 COIL CRYBA4 CSNK1G1 CUTC DCTD DZIP1L EAF1 EP400NL FAM90A1 GDAP2 GFAP HSPB7 ILVBL KIAA1143 KIAA1279 KLHDC4 LATS1 MAGEA11 MBD3 NHLRC2 PAICS PARD6B PIN1 PLCB1 POM121 RADIL RNF128 RPL9 SALL2 SH2D4A TBC1D27 TOB2 TSSC4 TTC21A TUFT1 TXNDC9 WDFY3 ZBTB24 ZMAT2 ZNF85
Entrez ID		54758	79959
HPRD ID		11180	12694
Ensembl ID		ENSG00000104731	ENSG00000101624
Uniprot IDs		Q8TBB5	B4DP81 Q8TAP6
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Chromatin Modification Chromatin Organization Negative Regulation Of Circadian Rhythm Histone H3-K9 Methylation Peptidyl-lysine Trimethylation Chromosome Organization Histone H3-K9 Modification Histone Modification Organelle Organization Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of Chromosome Organization Histone Lysine Methylation Regulation Of Circadian Rhythm Peptidyl-lysine Methylation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Primitive Erythrocyte Differentiation Cellular Response To Oxygen Levels G2/M Transition Of Mitotic Cell Cycle Histone Methylation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Microtubule-based Process Regulation Of Organelle Organization Protein Methylation Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Chromosome Organization Telomere Maintenance Via Telomere Shortening Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Peptidyl-lysine Modification Negative Regulation Of Telomere Maintenance Via Telomerase Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Response To Hypoxia Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Negative Regulation Of Gene Expression Rhythmic Process Replicative Cell Aging Positive Regulation Of Megakaryocyte Differentiation
Tagcloud ?			ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 rpgrip1 rpgrip1l tgl throw ttl
Tagcloud (Difference) ?			ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 rpgrip1 rpgrip1l tgl throw ttl
Tagcloud (Intersection) ?