KLHDC4

Description		kelch domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Hippocampal volume in mild cognitive impairment ( 29274321)
Interacting Genes		8 interacting genes: CEP76 KDM1A MFHAS1 SUV39H1 SUV39H2 TERF1 TRIM55 TRIM63
Entrez ID		54758
HPRD ID		11180
Ensembl ID		ENSG00000104731
Uniprot IDs		Q8TBB5
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3K9 Trimethyltransferase Activity Histone H3K9 Methyltransferase Activity Epigenetic Programming In The Zygotic Pronuclei Histone H3 Methyltransferase Activity Telomeric DNA Binding Epigenetic Programming Of Gene Expression Histone Methyltransferase Activity Chromosome Epigenetic Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of DNA Metabolic Process ENoSc Complex Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Cellular Response To Hypoxia Circadian Rhythm Cellular Response To Decreased Oxygen Levels Protein Demethylase Activity Chromosome, Centromeric Region Cellular Response To Oxygen Levels Negative Regulation Of Gene Expression, Epigenetic Chromatin Remodeling Methyltransferase Activity RDNA Heterochromatin Formation RDNA Heterochromatin Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Shelterin Complex Ankyrin Repeat Binding Chromosome, Telomeric Region Innate Immune Response Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Response To Fungicide MRF Binding Guanine Metabolic Process Diapedesis Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Histone H3K9me2 Methyltransferase Activity
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