CRLS1 and MCM7

Number of citations of the paper that reports this interaction (PMID 12771218)
15

Data Source:
HPRD (in vivo)

		CRLS1	MCM7
Gene Name		cardiolipin synthase 1	minichromosome maintenance complex component 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane	Chromatin Nucleoplasm Cytoplasm Cytosol Membrane MCM Complex
	Molecular Function	Phosphotransferase Activity, For Other Substituted Phosphate Groups	DNA Binding Single-stranded DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding
	Biological Process	Phospholipid Metabolic Process Cardiolipin Biosynthetic Process Phosphatidylglycerol Acyl-chain Remodeling Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication Cellular Response To DNA Damage Stimulus Cell Proliferation Regulation Of Phosphorylation Response To Drug Cellular Response To Epidermal Growth Factor Stimulus
Pathways		Acyl chain remodelling of PG Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Synthesis of CL	Synthesis of DNA G2/M Checkpoints Activation of the pre-replicative complex DNA Replication Pre-Initiation M/G1 Transition Regulation of DNA replication Activation of the pre-replicative complex Orc1 removal from chromatin S Phase DNA strand elongation Cell Cycle, Mitotic Assembly of the pre-replicative complex Orc1 removal from chromatin G1/S Transition Activation of ATR in response to replication stress Cell Cycle Checkpoints Removal of licensing factors from origins Mitotic G1-G1/S phases Switching of origins to a post-replicative state Unwinding of DNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: FBXO15 MCM6 MCM7 PINK1	59 interactors: AK8 APP ASB8 C8orf34 CCDC102B CCND1 CCNH CDC45 CDC6 CDC7 CDK7 CDKN1B CDT1 CRLS1 DBF4 FHL2 GOLGA2 HIF1A HIST3H3 IKBKG INTS6 KIFC3 MBIP MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM8 MCMBP MIPOL1 MNAT1 NAB2 NFKBIA ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PLK1 PNMA1 RAD17 RB1 RBL1 RBL2 RBM8A RPA1 SMC1A SNTA1 SP2 TCEB1 TREX1 TRIM27 TRIM54 UBE3A UBQLN1 USHBP1
Entrez ID		54675	4176
HPRD ID		12187	01154
Ensembl ID		ENSG00000088766	ENSG00000166508
Uniprot IDs		Q9UJA2	C6EMX8 P33993
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Unwinding Involved In DNA Replication DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation DNA Replication Initiation DNA Duplex Unwinding DNA Geometric Change DNA-dependent DNA Replication Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cellular Response To Hypoxia Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication DNA Conformation Change Positive Regulation Of Cellular Respiration Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Regulation Of Cellular Response To Hypoxia Positive Regulation Of Dopamine Secretion Peptidyl-serine Autophosphorylation Negative Regulation Of Oxidative Stress-induced Neuron Death TORC2 Signaling Positive Regulation Of Synaptic Transmission, Dopaminergic Positive Regulation Of Mitochondrial Fission Regulation Of Hydrogen Peroxide Metabolic Process Regulation Of Oxidative Phosphorylation Regulation Of Mitochondrion Degradation Positive Regulation Of Catecholamine Secretion Negative Regulation Of Hydrogen Peroxide-induced Cell Death Regulation Of Cellular Respiration Regulation Of Mitochondrial Fission Regulation Of Hydrogen Peroxide-induced Cell Death Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Organelle Organization Mitotic Cell Cycle Process Positive Regulation Of Protein Dephosphorylation TOR Signaling Regulation Of Dopamine Secretion Mitotic Cell Cycle Cellular Response To Toxic Substance Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Stress-induced Cell Death Response To Epidermal Growth Factor Mitochondrion Degradation	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Mitotic Cell Cycle Process DNA Replication Cell Cycle Cell Cycle Process DNA-dependent DNA Replication DNA Replication Initiation DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mitotic Cell Cycle Phase Transition Cellular Metabolic Process Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Cellular Response To DNA Damage Stimulus Cellular Response To Stress Chromosome Organization Regulation Of Kinase Activity Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cell Cycle Checkpoint Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Replication Checkpoint Positive Regulation Of Mitotic Cell Cycle DNA Duplex Unwinding DNA Geometric Change Regulation Of Phosphorylation Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Regulation Of Protein Kinase Activity Nucleotide-excision Repair, DNA Damage Removal Regulation Of Phosphorus Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Intracellular Receptor Signaling Pathway Metabolic Process
Tagcloud ?			aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?			aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?