CCSER2 and EXOC1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		CCSER2	EXOC1
Gene Name		coiled-coil serine-rich protein 2	exocyst complex component 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Cytoskeleton	Exocyst Cytosol Plasma Membrane Membrane
	Molecular Function	Microtubule Binding	Protein Binding
	Biological Process	Microtubule Bundle Formation	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS			Cervical cancer ( 23817570)
Protein-Protein Interactions		11 interactors: APP ATRX CRADD EXOC1 GTF2H1 MAP1LC3B NDEL1 OFD1 PSMD11 STX1A TCEA2	28 interactors: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST GOLGA4 KANSL1 KDM1A KIAA0226 KIAA1551 KIF5A LUC7L2 MACF1 NUF2 RALA RB1CC1 SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO
Entrez ID		54462	55763
HPRD ID		13832	07615
Ensembl ID		ENSG00000107771	ENSG00000090989
Uniprot IDs		Q9H7U1	Q9NV70
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle Signal Transduction In Response To DNA Damage Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Regulation Of Cell Cycle Process Cellular Component Assembly Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Process Axon Cargo Transport Positive Regulation Of Metabolic Process Mitotic Cell Cycle Positive Regulation Of Proteolysis DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Microtubule-based Movement Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To Stress Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To DNA Damage Stimulus Exocytosis Membrane Organization Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Developmental Cell Growth DNA-templated Transcription, Elongation Protein Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Mitotic DNA Damage Checkpoint Cell Cycle Process Forebrain Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Synaptic Growth At Neuromuscular Junction Regulation Of Cell Cycle Arrest Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Regulation Of Signaling Organelle Organization Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Collateral Sprouting In Absence Of Injury Cellular Response To Hydroxyurea Secretion By Cell Microtubule-based Transport	Golgi To Plasma Membrane Transport Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Locomotion Nervous System Development Post-Golgi Vesicle-mediated Transport Microtubule-based Process Regulation Of Cell Projection Organization Generation Of Neurons Regulation Of Autophagy TOR Signaling Organelle Organization Golgi To Plasma Membrane Protein Transport Neurogenesis Regulation Of Cell Size Regulation Of Cellular Component Size Chemotaxis Intracellular Signal Transduction Cellular Component Assembly Regulation Of Neuron Projection Development Vesicle-mediated Transport Autophagy Cellular Localization Axon Guidance Regulation Of Neurogenesis Positive Regulation Of Axon Extension Autophagic Vacuole Assembly Establishment Of Localization In Cell Regulation Of Primitive Erythrocyte Differentiation Lamellipodium Assembly Involved In Ameboidal Cell Migration Lamellipodium Assembly Microtubule Cytoskeleton Organization Cell Projection Organization Cell Communication Lamellipodium Organization Positive Regulation Of Neural Precursor Cell Proliferation Macroautophagy Cell Projection Morphogenesis Regulation Of Cell Development Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of SNARE Complex Assembly Cell Part Morphogenesis Cerebral Cortex Radially Oriented Cell Migration Axonogenesis Regulation Of Axon Extension Regulation Of Neuron Differentiation Regulation Of Organelle Organization Cell Cycle Response To External Stimulus Golgi Vesicle Transport
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