CCSER2 and OFD1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCSER2	OFD1
Gene Name		coiled-coil serine-rich protein 2	oral-facial-digital syndrome 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Cytoskeleton	Nucleus Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Membrane Centriolar Satellite Ciliary Basal Body
	Molecular Function	Microtubule Binding	Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding
	Biological Process	Microtubule Bundle Formation	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Embryonic Body Morphogenesis Axoneme Assembly Cilium Morphogenesis Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation
Pathways			Organelle biogenesis and maintenance Hedgehog 'off' state Assembly of the primary cilium G2/M Transition Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: APP ATRX CRADD EXOC1 GTF2H1 MAP1LC3B NDEL1 OFD1 PSMD11 STX1A TCEA2	8 interactors: CCSER2 EIF6 GPRASP1 KIAA1377 LUC7L2 NME7 PLK1 RUVBL1
Entrez ID		54462	8481
HPRD ID		13832	02162
Ensembl ID		ENSG00000107771	ENSG00000046651
Uniprot IDs		Q9H7U1	A6NF31 A8K2T9 E9KL37 O75665
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle Signal Transduction In Response To DNA Damage Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Regulation Of Cell Cycle Process Cellular Component Assembly Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Process Axon Cargo Transport Positive Regulation Of Metabolic Process Mitotic Cell Cycle Positive Regulation Of Proteolysis DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Microtubule-based Movement Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To Stress Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To DNA Damage Stimulus Exocytosis Membrane Organization Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Developmental Cell Growth DNA-templated Transcription, Elongation Protein Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Mitotic DNA Damage Checkpoint Cell Cycle Process Forebrain Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Synaptic Growth At Neuromuscular Junction Regulation Of Cell Cycle Arrest Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Regulation Of Signaling Organelle Organization Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Collateral Sprouting In Absence Of Injury Cellular Response To Hydroxyurea Secretion By Cell Microtubule-based Transport	Microtubule-based Process Microtubule Bundle Formation Organelle Organization Microtubule Cytoskeleton Organization Activation Of APC-Cdc20 Complex Activity G-protein Coupled Receptor Catabolic Process Cellular Macromolecular Complex Assembly Mitotic Cell Cycle Process Polar Body Extrusion After Meiotic Divisions Ribonucleoprotein Complex Assembly Mitotic Cell Cycle Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Cilium Organization Mature Ribosome Assembly Cellular Component Assembly Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Metaphase/anaphase Transition Of Mitotic Cell Cycle Ribosomal Subunit Export From Nucleus Cell Cycle Process Protein Localization To Chromatin Mitotic Nuclear Division Ribonucleoprotein Complex Biogenesis Cytoskeleton Organization Histone H2A Acetylation Cellular Localization Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Chromosome Segregation
Tagcloud ?			1x apparatus consequences depicted digital dimerization disclosed dramatically facial filaments focused golgi half homology implies imported lis1 lish localization localizations motif mutated nucleus oligomerization participate prediction solved tbl1 transducin
Tagcloud (Difference) ?			1x apparatus consequences depicted digital dimerization disclosed dramatically facial filaments focused golgi half homology implies imported lis1 lish localization localizations motif mutated nucleus oligomerization participate prediction solved tbl1 transducin
Tagcloud (Intersection) ?