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POLD2 and POLDIP2
Number of citations of the paper that reports this interaction (PubMedID
12522211
)
0
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
POLD2
POLDIP2
Description
DNA polymerase delta 2, accessory subunit
DNA polymerase delta interacting protein 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Zeta DNA Polymerase Complex
Delta DNA Polymerase Complex
Nucleus
Mitochondrion
Mitochondrial Matrix
Cell-cell Junction
Midbody
Mitochondrial Nucleoid
Mitotic Spindle
Molecular Function
DNA Binding
Protein Binding
DNA Binding
Protein Binding
Biological Process
DNA Replication
DNA-templated DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
DNA Damage Response
Error-prone Translesion Synthesis
DNA Biosynthetic Process
DNA Repair
DNA Damage Response
Mitochondrion Organization
Negative Regulation Of Macroautophagy
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Focal Adhesion Assembly
Error-free Translesion Synthesis
Mitotic Spindle Assembly
Positive Regulation Of Mitotic Cytokinesis
Vascular Associated Smooth Muscle Cell Proliferation
Pathways
Recognition of DNA damage by PCNA-containing replication complex
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Removal of the Flap Intermediate from the C-strand
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching
Removal of the Flap Intermediate
Processive synthesis on the lagging strand
Drugs
Diseases
GWAS
Osteoprotegerin levels (
25080503
)
Interacting Genes
19 interacting genes:
CCHCR1
CDK2
CDKN1A
EP300
ERBB2
KCTD13
LSM6
OGT
PCNA
POLD1
POLD3
POLD4
POLDIP2
POLDIP3
POLH
SOX12
WRN
WRNIP1
XRN1
19 interacting genes:
AGTRAP
ALAS1
APP
ASCC2
CPE
DNAAF6
DSCAM
FBXO7
HDAC6
MAD2L2
MTUS2
PCNA
PDPK1
POLD2
POLN
PTEN
REV1
SELENBP1
TAB1
Entrez ID
5425
26073
HPRD ID
15982
17874
Ensembl ID
ENSG00000106628
ENSG00000004142
Uniprot IDs
A0A087WWF6
P49005
B4DEM9
Q9Y2S7
PDB IDs
3E0J
6S1M
6S1N
6S1O
6TNY
6TNZ
9EKB
6Z9C
6ZLX
Enriched GO Terms of Interacting Partners
?
DNA Synthesis Involved In DNA Repair
DNA Biosynthetic Process
DNA Replication
Translesion Synthesis
DNA Damage Response
Postreplication Repair
DNA Repair
Delta DNA Polymerase Complex
Nucleus
Nucleobase-containing Compound Biosynthetic Process
DNA-directed DNA Polymerase Activity
Error-free Translesion Synthesis
Response To UV
Cellular Response To Radiation
Regulation Of DNA Metabolic Process
DNA Metabolic Process
Cellular Response To UV
Macromolecule Biosynthetic Process
Cellular Response To Light Stimulus
Positive Regulation Of DNA Replication
Cellular Response To Stress
Regulation Of DNA Replication
Nucleic Acid Metabolic Process
DNA-templated DNA Replication
Nucleoplasm
Damaged DNA Binding
Response To Light Stimulus
Chromosome, Telomeric Region
PCNA-p21 Complex
Nucleobase-containing Compound Metabolic Process
Response To Stress
Replication Fork
Mismatch Repair
Response To Radiation
Macromolecule Metabolic Process
Positive Regulation Of DNA Metabolic Process
Cyclin-dependent Protein Kinase Holoenzyme Complex
Nucleotide-excision Repair, DNA Gap Filling
Exonuclease Activity
MutLalpha Complex Binding
Telomere Maintenance Via Semi-conservative Replication
G-quadruplex DNA Binding
Cellular Senescence
Error-prone Translesion Synthesis
Regulation Of Metabolic Process
DNA Strand Elongation Involved In DNA Replication
Base-excision Repair, Gap-filling
Response To UV-C
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA Biosynthetic Process
Translesion Synthesis
Postreplication Repair
DNA Synthesis Involved In DNA Repair
DNA Biosynthetic Process
Error-prone Translesion Synthesis
DNA Replication
Zeta DNA Polymerase Complex
Neuron Projection Organization
DNA Repair
Response To Stress
Regulation Of Growth
DNA Strand Elongation Involved In DNA Replication
DNA Metabolic Process
Regulation Of Axon Extension Involved In Axon Guidance
Collateral Sprouting
Neuron Projection Morphogenesis
DNA Strand Elongation
DNA Damage Response
Cellular Response To Stress
Dendritic Spine Morphogenesis
Ubiquitin Binding
Cell Projection Morphogenesis
DNA-directed DNA Polymerase Activity
Positive Regulation Of Mitophagy
Regulation Of Developmental Growth
Positive Regulation Of Autophagy Of Mitochondrion
Macromolecule Metabolic Process
Central Nervous System Development
Positive Regulation Of Excitatory Postsynaptic Potential
Reproductive Behavior
Regulation Of Axonogenesis
Regulation Of Peptidyl-serine Phosphorylation
Dendritic Spine Organization
Macromolecule Biosynthetic Process
Amyloid-beta Complex
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Growth Cone Lamellipodium
Regulation Of Toll-like Receptor Signaling Pathway
Regulation Of Cell Projection Organization
Enzyme Binding
Regulation Of Response To Calcium Ion
Regulation Of Locomotion
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Regulation Of Cell Growth
PCNA Complex
Replisome
Response To Dexamethasone
3-phosphoinositide-dependent Protein Kinase Activity
Negative Regulation Of Synaptic Vesicle Clustering
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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