POLDIP2 and DNAAF6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POLDIP2	DNAAF6
Description		DNA polymerase delta interacting protein 2	dynein axonemal assembly factor 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cell-cell Junction Midbody Mitochondrial Nucleoid Mitotic Spindle	Cytoplasm Golgi Apparatus Trans-Golgi Network
	Molecular Function	DNA Binding Protein Binding	Protein Binding Dynein Intermediate Chain Binding Protein-folding Chaperone Binding
	Biological Process	DNA Repair DNA Damage Response Mitochondrion Organization Negative Regulation Of Macroautophagy Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Focal Adhesion Assembly Error-free Translesion Synthesis Mitotic Spindle Assembly Positive Regulation Of Mitotic Cytokinesis Vascular Associated Smooth Muscle Cell Proliferation	Cilium Movement Flagellated Sperm Motility Outer Dynein Arm Assembly Inner Dynein Arm Assembly Axonemal Dynein Complex Assembly
Pathways
Drugs
Diseases
GWAS		Osteoprotegerin levels ( 25080503)
Interacting Genes		19 interacting genes: AGTRAP ALAS1 APP ASCC2 CPE DNAAF6 DSCAM FBXO7 HDAC6 MAD2L2 MTUS2 PCNA PDPK1 POLD2 POLN PTEN REV1 SELENBP1 TAB1	16 interacting genes: ARID4B BTAF1 CCAR1 CDKL3 GAS2L2 KAT5 KIF13A MCM7 P2RX4 PID1 POLDIP2 PRKAA2 QRICH1 RNF39 TSEN15 YAF2
Entrez ID		26073	139212
HPRD ID		17874	06650
Ensembl ID		ENSG00000004142	ENSG00000080572
Uniprot IDs		B4DEM9 Q9Y2S7	Q9NQM4
PDB IDs		6Z9C 6ZLX
Enriched GO Terms of Interacting Partners?		Translesion Synthesis Postreplication Repair DNA Synthesis Involved In DNA Repair DNA Biosynthetic Process Error-prone Translesion Synthesis DNA Replication Zeta DNA Polymerase Complex Neuron Projection Organization DNA Repair Response To Stress Regulation Of Growth DNA Strand Elongation Involved In DNA Replication DNA Metabolic Process Regulation Of Axon Extension Involved In Axon Guidance Collateral Sprouting Neuron Projection Morphogenesis DNA Strand Elongation DNA Damage Response Cellular Response To Stress Dendritic Spine Morphogenesis Ubiquitin Binding Cell Projection Morphogenesis DNA-directed DNA Polymerase Activity Positive Regulation Of Mitophagy Regulation Of Developmental Growth Positive Regulation Of Autophagy Of Mitochondrion Macromolecule Metabolic Process Central Nervous System Development Positive Regulation Of Excitatory Postsynaptic Potential Reproductive Behavior Regulation Of Axonogenesis Regulation Of Peptidyl-serine Phosphorylation Dendritic Spine Organization Macromolecule Biosynthetic Process Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization Growth Cone Lamellipodium Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Cell Projection Organization Enzyme Binding Regulation Of Response To Calcium Ion Regulation Of Locomotion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Cell Growth PCNA Complex Replisome Response To Dexamethasone 3-phosphoinositide-dependent Protein Kinase Activity Negative Regulation Of Synaptic Vesicle Clustering	Lipid Droplet Disassembly Phosphatidylethanolamine Biosynthetic Process Positive Regulation Of Biosynthetic Process Phosphatidylethanolamine Metabolic Process Phosphatidylcholine Biosynthetic Process CGAS/STING Signaling Pathway
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