POLDIP2 and SELENBP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLDIP2	SELENBP1
Gene Name		polymerase (DNA-directed), delta interacting protein 2	selenium binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Nucleoid	Extracellular Space Nucleolus Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding	Protein Binding Selenium Binding
	Biological Process	Mitochondrion Morphogenesis	Protein Transport
Pathways
Drugs
Diseases
GWAS			Blood trace element (Cu levels) ( 23720494)
Protein-Protein Interactions		14 interactors: ALAS1 APP ASCC2 CPE HDAC6 MAD2L2 MTUS2 PCNA PDPK1 POLD2 POLN REV1 SELENBP1 TAB1	12 interactors: BARD1 EED GORASP2 GPX1 LRIF1 MED31 MLH1 POLDIP2 RPA1 TRA2A TRIP13 USP33
Entrez ID		26073	8991
HPRD ID		17874	05007
Ensembl ID		ENSG00000004142	ENSG00000143416
Uniprot IDs		Q9Y2S7	A6PVW9 Q13228
PDB IDs
Enriched GO Terms of Interacting Partners?		Translesion Synthesis Postreplication Repair DNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Nitrogen Compound Metabolic Process DNA Repair DNA Replication Response To Stress Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA-dependent DNA Replication Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Cellular Response To DNA Damage Stimulus Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Nucleobase-containing Compound Metabolic Process DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening DNA Metabolic Process Cellular Macromolecule Biosynthetic Process Biosynthetic Process Macromolecule Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Transcription-coupled Nucleotide-excision Repair DNA Recombination Cellular Metabolic Process Cellular Response To Stimulus Mismatch Repair Base-excision Repair Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Deoxyribonuclease Activity Hsp90 Deacetylation Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Proteolysis Telomere Maintenance Regulation Of Catalytic Activity Negative Regulation Of Protein Processing Negative Regulation Of Protein Metabolic Process Positive Regulation Of Chaperone-mediated Protein Complex Assembly Leading Strand Elongation Synaptic Growth At Neuromuscular Junction Polyubiquitinated Misfolded Protein Transport Nucleotide-excision Repair Regulation Of Protein Processing Positive Regulation Of Cellular Metabolic Process	Cell Cycle Cellular Response To Stress Nucleobase-containing Compound Metabolic Process Double-strand Break Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Meiotic Nuclear Division Cell Cycle Process Cellular Nitrogen Compound Metabolic Process Meiotic Cell Cycle DNA Repair DNA Recombination Multicellular Organismal Homeostasis Nitrogen Compound Metabolic Process Reciprocal Meiotic Recombination Organelle Organization Synapsis Mismatch Repair Homologous Chromosome Segregation Male Meiosis Meiotic Spindle Midzone Assembly Positive Regulation Of Fibril Organization Meiotic Metaphase I Plate Congression Cellular Response To DNA Damage Stimulus Oogenesis Meiotic Chromosome Segregation Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Recombination Negative Regulation Of MRNA 3'-end Processing Response To Symbiotic Bacterium Chromosome Organization Meiosis I Aromatic Compound Catabolic Process Female Gamete Generation DNA Metabolic Process Regulation Of Fibril Organization Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Response To Lipid Hydroperoxide DNA Recombinase Assembly RNA Metabolic Process Myoblast Proliferation Negative Regulation Of Protein Export From Nucleus Protein Oxidation Response To Selenium Ion Tissue Homeostasis Response To Stress Gene Expression Protein K6-linked Ubiquitination Intrinsic Apoptotic Signaling Pathway
Tagcloud ?		atherosclerosis cdk1 curves cyclina2 delta die doubling e2f elongation embryos heterozygous homozygous lc3b mefs nox4 originally p21cip1 partner passage pcna proliferating restenosis s20 sirt1 sv40 transfection unaffected underline understudied	aci arthritis ccl2 chemicals cia10 cia25 cia3d cia5a cigarette clec4m congenic congenics core correlating da erosive f344 mediators nonerosive nongenetic nongenetically rheumatoid scd1 slc7a10 spond1 synovial tnn upstream xenobiotic
Tagcloud (Difference) ?		atherosclerosis cdk1 curves cyclina2 delta die doubling e2f elongation embryos heterozygous homozygous lc3b mefs nox4 originally p21cip1 partner passage pcna proliferating restenosis s20 sirt1 sv40 transfection unaffected underline understudied	aci arthritis ccl2 chemicals cia10 cia25 cia3d cia5a cigarette clec4m congenic congenics core correlating da erosive f344 mediators nonerosive nongenetic nongenetically rheumatoid scd1 slc7a10 spond1 synovial tnn upstream xenobiotic
Tagcloud (Intersection) ?